Dissertation > Excellent graduate degree dissertation topics show

Effects of Aerobic Exercise on the Expression of the Visfatin Gene and Protein in Obesity Rat Adipose Tissue

Author: ShangGuanZuo
Tutor: FengFeiHu
School: Wuhan Institute of Physical Education
Course: Sports Medicine
Keywords: Aerobic endurance exercise high fat diet visceral adipose tissue fat visfatin
CLC: G804.2
Type: Master's thesis
Year: 2012
Downloads: 112
Quote: 0
Read: Download Dissertation

Abstract


Objective:Long-term aerobic ran a movement observation to the fat rat lipid levels and visceral fat tissue visfatin gene and protein expression level influence and discuss the possible mechanism, to provide a theoretical basis for the motion to reduce weightMethods:By four weeks of age60male Sprague-Dawley rats were randomly divided into two groups, control group10:general feeding, high fat diet group50. Respectively using common feed and high fat feed for feeding. After high fat feeding7weeks founding obesity model in16rats, and then they were randomly divided into two groups (n=8):obesity does not exercise group (OW), obesity exercise group (OW-E), the beginning of the eighth week of exercise intervention. During treadmill exercise, all rats were fed with common feed. Combining exercise with the nutrition intervention group exercise program:a rat for electric treadmill, the slope of5degrees, the speed of15.2m/min, a64+4.5%VO2max strength, and electric drive. Exercise duration of60minutes,6times per week, Sunday rest, lasted eight weeks. In the last training session and after12hours of fasting, the rats with2%sodium pentobarbital intraperitoneal anesthesia, blood from the heart, isolated from the serum, quickly removed perirenal adipose tissue and testis of perirenal fat tissue and weighing, with aluminum foil wrap, plunged into liquid nitrogen frozen, then transferred to-80degrees C refrigerator. Statistical analysis using the13edition of SPSS statistical software. The results for" mean+SD"(x+s) said. Statistical analysis using the single factor analysis of variance and independent sample t test. P<0.05is expressed as significant difference, P<0.01is shown as a very significant difference.Result:1. High fat diet can induce experimental rats happen simple obesity, and cause dyslipidemia.2. Visfatin express degree:Control group significantly (P<0.05) less than OW, OW group-group E significantly (P<0.05) less than OW group.3. Internal fat mass:OW group of internal fat mass higher than group C, has a very significant difference (P<0.01); OW-E group internal fat content significantly lower than OW group (P<0.05).4. Three group of big lies in fat tissue protein level visfatin no significant difference (P>0.05).5. Internal fat tissue visfatin mRNA gene expression quantity and internal fat positive correlation between quantity (r=0.48, P<0.05).Conclusion:1:High fat diet can induce experimental rats happen simple obesity, and cause dyslipidemia.2. Big lies inside adipose tissue visfatin mRNA expression of visceral fat with the increase of number and visceral fat volume a positive correlation (r=0.48, P<0.05).3. Long-term aerobic exercise significantly reduced visceral fat tissue visfatin mRNA expression (P<0.05); But for internal fat tissue protein expression level visfatin has no significant effect (P>0.05).4. Long-term aerobic exercise can reduce high fat feed of rats induced obesity of serum TG (P<0.05), increase HDL-C (P<0.05), so as to improve blood lipid levels.

Related Dissertations

  1. Clincial Research on Xue Mai Kang Decoction on Blood Fat of Hyperlipidemia Phlegm Turbility and Blood Stasis Hyperlipidemia Patients,R259
  2. Effects of Different Reconciled Corn Oils on Antioxidative Stress, Lipid Metabolism Enzymes, and Abundance of Immune-related Genes of Broilers,S831.5
  3. Effects of Dietary Oil Sources on Growth Perfomance, Lipid Deposition and Blood Biochemical Index of Carassius Auratus Gibelio,S963.1
  4. Apolipoprotein E Gene Knock-out and High-fat Diet on IP3、 IP3R-1 & Aβ Expression in Neurons of Mice’s Hippocampal CA1 & Ca3,R329
  5. The Expression of Visfatin in Liver of Rats in Different Glucose Metabolic Statuses and Effects to Glucose and Energy Metabolism,R587.1
  6. Improvement of the Result of Autologous Fat Transplantation in Facial Recontouring Surgery by Using "Cocktail" Therapy,R622
  7. Clinical Effect of Autologous Fat Pellet Particle Transplanting Combined Ligustrazine on Breast Augmentation,R622
  8. Orbital fat orbital Bow release lower eyelid blepharoplasty with conventional surgical rejuvenation effect is,R622
  9. Swelling commonly used lidocaine and epinephrine on fat cell activity,R622
  10. Percutaneous cardiopulmonary support the treatment of swine Efficacy of fulminant fat embolism syndrome,R614
  11. Clinical Research of Autogenous Fat Transplantation by Injection to Improve Nasolabial Depress.,R622
  12. The Application of STIR-FLAIR and T2W-SPIR for Diagnosing the Orbital Lesions: a Contrast Study,R777
  13. Effects of Phenol on Digestive Function of Moina Macrocopa,X174
  14. Study on Lipolysis Change on Sufu during the Fermentation Process,TS214.2
  15. Visfatin Enhances ICAM-1 and VCAM-1 Expression Under Lps Treatment in Rat Cadiocyte,R363
  16. The Related Research between Body Fat Percent and BMI in Huazhong University of Science and Technology,G804.49
  17. The Relationships among Osteopontin, Obesity and Insulin Resistance,R589
  18. Preparation and Application of Porous Matrix Phase Change Materials for Thermal Storage in Building Energy Conservation,TB34
  19. The Changes and Influential Factors of Adiponectin、Apelin and Visfatin in Coronary Heart Disease Patients Accompanied with Abnormal Glucose Metabolism,R587.1
  20. To Researched the Impact of Rosuvastatin on Adiponectin, Visfatin and High Sensitivity C-reactive Protein in Patients with Metabolic Syndrome,R589
  21. The Effects and Machanism of Cholesterol Overload on Visfatin Secretion from Adipocytes,R589.2

CLC: > Culture, science,education, sports > Sports > Sports theory > Fundamental Physical Science > Exercise Physiology
© 2012 www.DissertationTopic.Net  Mobile