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The Clinical Study of Yiqihuayu Capsule in the Treatment of Unstable Angina Pectoris and Its Effect on hs-CRP

Author: ZhaoYuQin
Tutor: ZhangShiLiang
School: Shandong University of Traditional Chinese Medicine
Course: Chinese medical science
Keywords: Yiqi huayu capsule Unstable angina Deficiency of qi and bloodstasis High-sensitivity C-reactive Protein
CLC: R259
Type: Master's thesis
Year: 2013
Downloads: 21
Quote: 0
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Abstract


Purpose: Serum hypersensitive C reactive protein (hs-CRP) has become the predictorof risk factors of coronary heart disease and cardiovascular events. To observe the YiqiHuayu Capsule in the treatment of unstable angina pectoris and protein on hypersensitiveC reaction (hs-CRP) has any effect, clinical research so we designed "Yiqi Huayu Capsulein treating unstable angina pectoris of coronary heart disease and its influence on thehs-CRP", to further explore the mechanism of Yiqi Huayu Capsule in the treatment ofcoronary heart disease.Methods:The coronary angiography or coronary CT examination confirmed thediagnosis of coronary artery disease,60patients with chest pain and diagnostic criteria ofQi and blood stasis, were randomly divided into experimental group30cases, controlgroup30cases. The experimental group and the control group were treated with routinewestern medicine therapy, the experimental group treated with Yiqi Huayu capsule,4weeks as a course of treatment, comparing the changes before and after treatment in twogroups of patients symptoms, signs, clinical manifestations of angina pectoris,electrocardiogram, TCM syndrome, hs-CRP index.Results:Yiqi Huayu capsule has the effect of Supplementing Qi and activating bloodcirculation, removing blood stasis and relieving pain. Treatment of angina pectoris ofcoronary heart disease, can alleviate the clinical symptoms such as chest tightness; canregulate blood lipids, improve the blood rheology, improve myocardial ischemia, withoutobvious adverse reaction after treatment. At the same time also significantly reduceshypersensitivity in patients with serum level of C reactive protein, prompting mechanismof Yiqi Huayu Capsule in the treatment of unstable angina pectoris may be adopted toreduce inflammation, reduce the level of serum hs-CRP to achieve.Conclusion:Yiqi Huayu capsule can obviously relieve chest pain, chest tightness and other clinical symptoms, can regulate blood lipids, improve the blood rheology, improvemyocardial ischemia, without obvious adverse reaction after treatment. At the same timealso significantly reduces hypersensitivity in patients with serum C reactive protein level,suggesting the possible mechanism of Yiqi Huayu Capsule in the treatment of unstableangina pectoris and decrease the level of serum hs-CRP, the inflammatory response.

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