Dissertation > Excellent graduate degree dissertation topics show

The Neural Mechanisms Underlying the Effects of Acute Restraint Stress on Bee Venom-induced Nociception and Inflammation

Author: WenWeiWei
Tutor: HeXiang
School: Dalian Medical University
Course: Neurology
Keywords: Inflammatory pain bee venom acute restrain stress endogeneous opioid system sympathetic nervous system capsaicin-sensitive primary afferent fibers
CLC: R363
Type: Master's thesis
Year: 2006
Downloads: 43
Quote: 0
Read: Download Dissertation

Abstract


Background and purpose: Inflammation caused by peripheral tissue injury produces pain-related behavior (persistent spontaneous nociception and hyperalgesia) and inflammatory reaction such as redness and edema. Inflammation can be divided into neurogenic and histogenic process. Inflammation triggered by substances released from sensory nerve terminals is referred to as“neurogenic inflammation.”Nociceptive impulses also can be antidromically transmitted into the peripheral nerve terminals when they are sent to the spinal cord from the injury site. The process is generally attributed to the release of substance P(SP) and calcitonin gene-related peptide(CGRP) mediated by axon reflex and/or dorsal root reflex. These inflammatory mediators then induce or promote the dilation of peripheral blood vessels and the inflammation processes. Histogenic inflammation refers to the process that local insults cause the release of a lot of inflammatory mediators such as bradykinin、prostaglandin E2、5-HT、histamine and cytokinin which promote the development of inflammation. Clinical inflammatory pain is characterized as persistent spontaneous pain, thermal and mechanical hyperalgesia. Inflammatory pain is generally resulted from the sensitization of peripheral nociceptors and central neurons.Acute stress alone can induce analgesia and cause an inflammatory response. Stress is closely linked to our most primitive biological pathways,

Related Dissertations

  1. The Treatment Effect and Mechanism of Ketanserin on Inflammatory and Neuropathic Pain,R741
  2. SP and NK-1 Receptor Promote Activation of Astrocytes in the Dorsal Horn of Spinal Cord during Nociceptive Inputs of Rats,R363
  3. The Influence of Analgesia Effect of Electroacupuncture Combined with Fentannyl on Chronic Inflammatory Rats,R614
  4. Studies on the Chemical Constituents and Bioactivites of Two Medicinal Plants of Leontopodium Longifolium and Dracocephalum Tanguticum,R284
  5. The Experimental Study on Antinociceptive Efficacy of Pre-emptive Intrathecal Administration of CRH and Its Expression in Dorsal Horn of Spinal Cord during Formalin-induced Inflammatory Pain,R402
  6. The Effect of Acute Experimental Hyperglycaemia on Pain Sensitivity of Rats,R587.1
  7. Changes of the Somatosensory Evoked Potential and Brainstem Audiotory Evoked Potentials in Formalin Induced Inflammatory Pain and Hyperalgesia of Rats,R363
  8. Nociceptive Input Induces Increases of Nitric Oxide Synthase Expression and Nitric Oxide Production in Rat Hippocampus,R363
  9. Composition of iNOS Immunoreactive Cells in the Spinal Dorsal Horn during Formalin Induced Inflammatory Pain,R363
  10. The Role of β-adrenergic Receptors in Osteogenesis and Adipogenesis of Mouse Mesenchymal Stem Cells,Q57
  11. Study on the Molecular Mechanisms of Spinal Macrophage Migration Inhibitory Factor (MIF) in the Pathogenesis of Pain,R363
  12. The Potential Role of Calpain in the Zymosan-Induced Paw Inflammatory Pain Rats,R402
  13. Intra-cerebroventricular Injection of Anti-somatostatin-serum Involved in the Inflammatory Pain and Electro-Acupuncture Analgesia in Rats,R246.2
  14. Spinal Cord 5-Hydroxytryptamine1A Receptor is Involved in Descending Facilitating Nociception,R33
  15. Inhibition of the Expression of Nav1.8 by RNA Interference in Pain Study,R614
  16. The Experiment Study of ERK Inhabitor on the Analgesic Effect and Mechanisms in CFA-induced Rat Pain Model,R614
  17. Modulation of Glycine Site of NMDA Receptor Contributes to the Integration of Nociceptive Processing in the Spinal Cord and Anterior Cingulate Cortex,Q42
  18. The Mechanisms of NMDA Receptor NR2B Subunit in the Spinal Cord of Inflammatory Rats,R402
  19. Role of GABA_B Receptors in Pain Regulation at the Spinal Level,R33
  20. Involvement of Spinal Orphanin FQ/Nociceptin in Inflammatory Pain and Electroacupuncture Analgesia in Rats,R245
  21. Experimental Studies on Anti-hyperalgesia Mechanism of Ketamine,R614

CLC: > Medicine, health > Basic Medical > Pathology > Pathophysiology
© 2012 www.DissertationTopic.Net  Mobile