Dissertation > Excellent graduate degree dissertation topics show

Study of the Polymethoxylated Flavonoids in Fructus Aurantii Immaturus

Author: YangZuoZuo
Tutor: WangEnSi
School: Jilin University
Course: Medicinal Chemistry
Keywords: Citrus aurantium HPLC Multi methoxyflavone Anticancer Purification Synthesis
CLC: R284
Type: Master's thesis
Year: 2007
Downloads: 518
Quote: 1
Read: Download Dissertation

Abstract


Purpose: with anticancer activity of acid-insoluble ash methoxy flavone ingredients to study more, to Chinese medicine chemical separation and structural identification of acid-insoluble ash and acid-insoluble ash are quality standards research, using the method of synthesis of synthesis of a series of methoxy flavone compounds and use more chicken embryo villus allantois membrane (CAM) model was developed for the determination of methoxy flavone compounds more antitumor activity. Methods: silica gel column chromatography was used to traditional Chinese medicine (TCM) chemical components of acid-insoluble ash separation, using HPLC to the quality standard of frutus aurantii immaturus, using the method of synthesis of synthesis of a series of methoxy flavonoids, and through 1 h - NMR, 13 c - NMR and MS for structure identification, separation and synthesis of the compounds with CAM to determine the antitumor activity. Results: the separation of seven flavonoids were identified, and immature bitter orange quality standards research, identified four flavonoids synthesis, through the CAM model anti-cancer activity determination results is better. Conclusion: methyl hesperidin was first isolated from immature bitter orange, immature bitter orange HPLC to control the quality of simple operation, good separation effect, high sensitivity, good repeatability.

Related Dissertations

  1. Studies on the Synthesis and Technology of Dipentaerythritol and Its Derivative,TQ223.164
  2. Synthesis and Characterization on Semi-Aromatic Polyamides Containing Benzoxazole Units,O633.5
  3. Hydrothermal Synthesis of Oxide Hollow Spheres,TB383.4
  4. Study on Protective Effects of Apple Polyphenol on Immune System Injury Caused by γ-Ray,S661.1
  5. Video Coding Research Based on Texture Characteristics,TP391.41
  6. Poetic alienation : graphics,J506
  7. Study on Wastewater Purification Effect of the Free Surface Wetland with Different Substrates and Plant Combination,X703
  8. Urothermal Synthesis, Structure and Characterization of Functional Coordination Polymers,O631.3
  9. Studies on Fermentation Optimization, Purification and Enzyme Characteristics of Lipase from Aspergillus Oryzae FS-1,TQ925.6
  10. Studies on Isolation, Purification and Chemical Structure for Polysaccharides from Camellia Chrysantha(Hu) Tuyama,S567.19
  11. The Total Synthesis of a Flavonoid Glycoside Apigenin-7-O-β-D-glucuronide,R284.1
  12. Study on the Preparation of the Low Molecular Weight Fuciodan from Sargassum Henslowianum (C.Agardh) and Anti-tumor Activity,TS254.9
  13. Study on the Pharmacokinetics of Xiaoaiping and Chlorogenic Acid in Rats and the Quality Standard of Xiaoaiping Preparations,R285
  14. Synthesis and Seperation of 1,1’-binaphthol,O625.3
  15. Studies on Extraction and Analysis of Fructooligosaccharides in Smallanthus Sonchifolius,TS255.1
  16. Flexible,rigid,Synthesis and characterization of mixed ligand complexes,O621.1
  17. Synthesis and Performance Study of Bisphenol AP-based Polybenzoxazines,TQ320.1
  18. Experiment Study of the Biogas Purification Process by Zeolite Filling Washing,TQ221.11
  19. Isolation Entophytes and Study on the Fermentation of Bacillus Subtilis tiD7 from Rehmannia,TQ461
  20. Optimization of Fermentation Conditions, Purification, Cloning and Expression of a Cold-active Lipase from Pseudomonas Sp.RT-1,TQ925
  21. Study on the Synthetic Process of Vat Pink R,TQ616.2

CLC: > Medicine, health > Chinese Medicine > Of Pharmacy > Traditional Chinese medicine chemical
© 2012 www.DissertationTopic.Net  Mobile