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Pharmaceutical Studies on Jiakang Granule

Author: DongLin
Tutor: LiYanBing
School: Heilongjiang University of Traditional Chinese Medicine
Course: Pharmaceutical Analysis
Keywords: Hyperthyroidism particles Preparation Process Quality standards Ursolic acid
CLC: R286
Type: Master's thesis
Year: 2007
Downloads: 119
Quote: 0
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Abstract


Hyperthyroidism is a common endocrine disease of an organ-specific autoimmune diseases . Its occurrence directly related to genetic and immune factors . According to statistics, about 14 million patients with hyperthyroidism , and increased , and seriously affect the quality of people's lives . The subject in order to the doctors experience side topics for the to facilitate medication, improve drug stability , decoction prepared the granules - hyperthyroidism particles , Attending functions of the compound of the nature of the binding component herbs taste and modern research , hyperthyroidism particles preparation process and quality standards . (A ) Study on Preparation 1 . Prunella , Bupleurum , turmeric volatile oil extraction and β - CD inclusion ; 2 . Alcohol extraction technology research ; 3 . Water extraction ; 4 . Water extraction and alcohol precipitation process research . Prunella , Bupleurum , turmeric volatile oil inclusion study of existing literature reported inclusion method validation; alcohol extract water refers to water extraction and alcohol precipitation process mainly through orthogonal experiment method screening the best extraction process, in which alcohol extraction process of ursolic acid as index , water extraction and water extraction and alcohol precipitation process as index paeoniflorin . ( B) Quality Standard of turmeric , Fritillaria, forsythia qualitative identification of the thin layer ; selection of ursolic acid content determination for Evaluation measured recovery rate was 98.44% , the content is not less than 0.174mg · g -1 ; controllable through preliminary stability tests proved process is reasonably practicable , the quality of the basic stability .

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CLC: > Medicine, health > Chinese Medicine > Of Pharmacy > In drugs
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