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Cold feel the wind cold or when the virus, causing the dysfunction of lung health, nasal congestion, runny nose, sneezing, headache, chills, fever, general malaise and other clinical manifestations of exogenous disease. The clinical manifestations of Shushi cold is different from the common cold, and hard to be cured, treatment is quite difficult. Mannose disinfection pill first set out in the \In accordance with the requirements of the modern new Chinese medicine for status of nectar disinfection pills, using modern extraction and purification, the modern quality detection technology and preparation techniques, modern pharmacodynamic and toxicological research methods, a systematic study of the nectar disinfection capsules. Through its extraction process, the transfer rate as an indicator cream rate and forsythin content, orthogonal design the alcohol extraction process has been optimized to volatile oil yield, cream, baicalin content as an indicator, using single factor and orthogonal test method to optimize the water extraction and alcohol precipitation process determine the optimum the mannose disinfection capsules; preparations Betacyclodextrin volatile oil inclusion, to ensure product quality stable, and the preparation of the molding process, taking into account taking necessary preparations molding, the optimized preparation process. Through the mannose disinfection capsules quality standards, developed mannose disinfection capsule quality standards. Using thin-layer chromatography the Shichangpu, cardamom, forsythia, Sichuan Fritillaria four flavor Smell the qualitative identification of the thin layer, using high-performance liquid chromatography to determine the content of baicalin and water, disintegrating, heavy metals, arsenic salt and other checks, the use of of sample observation law visits nectar disinfection capsule the stability of the finished product. The standard is high sensitivity, accuracy, repeatability, specific, and can effectively control the quality of their products. Mannose disinfection capsules xylene-induced mouse ear edema and increased capillary permeability in mice induced by acetic acid to observe the anti-inflammatory effects; hot-plate and writhing observe the analgesic effect; endotoxin-induced fever and dry yeast-induced fever rats to evaluate the antipyretic effect; A / PR 8/34 influenza viruses evaluation of its antiviral activity, results showed that the mannose disinfection capsule has significant anti-inflammatory, analgesic, antipyretic, anti-viral effect, and quite capsules in the original dosage form and the same dose of drug action. Mannose disinfection capsule system research, the formulation process is reasonable, stable and viable, stable and controllable quality, pharmacological effects, in line with the modern traditional Chinese medicine requirements.
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