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Effects of Trace Element and Blood Lead Level on Health of 1300 Children

Author: YangZuoQing
Tutor: LouXiaoMin;YaoWu
School: Zhengzhou University
Course: Child and adolescent health and maternal and child health science
Keywords: Trace elements Child Health Lead poisoning Iron deficiency anemia
CLC: R179
Type: Master's thesis
Year: 2008
Downloads: 107
Quote: 2
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Abstract


The purpose of trace elements form the basis of human life substances, is the body's development, an essential element of life activity and reproduction. Human body trace elements, although small amounts, but to human health but plays an important role. They convert the energy of the body, hormone synthesis, brain and memory, visual acuity, are affected, but also involved in the body's cell division, a variety of metabolic, endocrine and immune process. When a trace element in the human body insufficient intake or excessive, will cause the body's biological dysfunction, have adverse effects on the human body. Animal experiments, epidemiological investigation and clinical observation and treatment have confirmed that the trace elements associated with many diseases. Children are the individual is in the growth and development stage of growth, relatively sensitive to changes in the external environment, in order to understand the trace elements iron, zinc, calcium, magnesium, copper, lead levels and six trace elements in the blood of children in Zhengzhou City mutual investigate the relationship between blood trace elements iron, zinc, calcium, magnesium, copper, lead level of children's growth and development retardation and early childhood health status of the relationship, the Maternal and Child Health Hospital of Zhengzhou City in June 2004 to 2006 month examination and outpatient better 1 month to 15-year-old child's health records and medical records information discussed to provide a scientific basis for the study of children's health care and related diseases prevention and control measures. Methods Maternal and Child Health Hospital of Zhengzhou City in June 2004 to the June 2006 examination and outpatient cases the information better 1 month to 15-year-old child's health records and medical records, a total of 1300 cases, including data collection study demographic characteristics (such as name, sex, date of birth, age, place of residence, etc.); personal development (height, vision, IQ is normal, whether learning disabilities, whether retardation, whether malnutrition); personal health (repeated respiratory tract infection, rickets, attention deficit hyperactivity disorder, anemia, etc.) and meals. Children's blood iron, zinc, calcium, magnesium, copper, lead levels of trace elements measured using atomic absorption spectrometry detection. SPSS12.0 statistical analysis and test of significance. 1 children five kinds of trace elements and the average blood lead were within the normal range: blood iron of 9.17 ± 0.08μmol / L, serum zinc to 76.53 ± 4.21μmol and / L, calcium 1.75 ± 0.55 mmol / L, serum magnesium was 1.50 ± 0.06 mmol / L, serum copper was 20.23 ± 1.37μmol / L and blood lead to 64.79 ± 12.63μg / L. The boy's blood lead levels were significantly higher than that of girls. The Baby group of blood iron, serum zinc, mean blood lead was significantly lower than other age groups (P <0.01). (2) the lack of children trace elements calcium deficiency (lack of 24.46%), iron deficiency (lack of 21.77%), zinc deficiency (lack of 19.69%) as the main lead poisoning rate (19.08%), magnesium deficiency was 1.46 % copper deficiency rate of 3.85%. Boys the blood zinc deficiency rate significantly higher than that of girls, the difference was statistically significant (P <0.01), the boys lead poisoning detection rate was significantly higher than that of girls, the difference was statistically significant (P <0.01). 3 children trace elements iron and copper, zinc and copper, iron, zinc and calcium and lead the interactions between. Children with lead poisoning blood iron, serum zinc and serum calcium levels were significantly lower than children in the control group (P <0.01). Iron deficiency anemia (IDA), the prevalence of up to 20.07%; recurrent respiratory tract infection prevalence rate of 23.36%, amblyopia prevalence rate of 7.27% was no significant difference in the prevalence of various age groups (P> 0.05 ). ADHD prevalence rate of 6.29%, the the ADHD high incidence in preschool and school-age group; rickets prevalence of 6.11%, high in the group of infants, toddlers group and preschool group. School-age group, the highest rate of lead poisoning in children, pre-school group, followed by a slightly lower group of children, the baby was the lowest. 5 children with short stature group serum zinc, serum calcium levels significantly lower than the control group (P <0.05), rickets in children in blood zinc, blood iron levels were significantly lower than the control group (P <0.05), children's group serum zinc recurrent respiratory tract infections, serum iron and serum calcium levels were significantly lower than the control group (P <0.05), children with ADHD serum zinc and serum copper levels were significantly lower than the control group (P <0.05), iron deficiency anemia in children's blood iron, serum zinc and serum copper levels children with amblyopia only blood zinc levels were significantly lower than the control group (P <0.01) were significantly lower than the control group (P <0.05),. Children with short stature, rickets in children with recurrent respiratory tract infections children, children with ADHD, children with iron deficiency anemia and mental retardation in children's blood lead level was significantly higher than that in the control group, the difference was statistically significant (P <0.01). Conclusions of this study object micronutrient deficiencies in calcium, iron, zinc. The rate of lead poisoning in children up to 19.08%, lead poisoning in children's blood iron, zinc blood, serum calcium levels were significantly lower than the control group children. 2 recurrent respiratory tract infections in children, the incidence of attention deficit hyperactivity disorder, iron deficiency anemia, children with short stature, rickets and children's blood zinc levels significantly lower blood lead levels were significantly elevated; elevated blood lead levels in children with mental retardation related; amblyopia children in blood zinc levels were significantly reduced. Iron deficiency anemia (IDA), repeated respiratory infections children, rickets in children's blood iron levels were significantly lower than the control group, while the children of short stature, recurrent respiratory tract infections children calcium level lower.

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CLC: > Medicine, health > Preventive Medicine,Health > Children,youth health
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