Dissertation > Excellent graduate degree dissertation topics show

Research on Coupling Reactions Catalyzed by Cu

Author: XuZhen
Tutor: ZengRunSheng
School: Suzhou University
Course: Organic Chemistry
Keywords: copper(II) ions CuI nanoparticles tandem cross-coupling reaction A3- coupling guanidinylation
CLC: O643.32
Type: Master's thesis
Year: 2011
Downloads: 95
Quote: 0
Read: Download Dissertation

Abstract


The transition metal-catalyzed cross-coupling reactions to form sp2 C-C or C-heteroatom bonds have received considerable attention in the past dexades. In comparision with Pd and Ni, copper is a cheaper metal with lower toxicity.1.A Copper(II)-Catalyzed Tandem Synthesis of Substituted 3-Methyl Eneisoindolin -1-onesCu(OAc)2·H2O/2, 2’-biimidazole catalyzed coupling of 2-iodobenzamides (or 2-bromobenzamides) and terminal alkynes in DMF at 60°C and subsequent additive cyclization produces substituted 3-methyleneisoindolin-1-ones. This reaction system was novel, mild and efficient.2. Palladium- and ligand-free Sonogashira reaction catalyzed by CuI nanoparticles An efficient CuI nanoparticles catalyzed Sonogashira-type coupling reaction of aryl halides with terminal alkynes is described. The couplings could be successfully carried out in the absence of the palladium, ligands and any activator. The desired products are isolated in good yields (up to 99%).3. Research on the three component coupling reaction of aldehyde、alkyne and amine catalyzed by CuI nanoparticles A highly efficient catalyst, CuI nanoparticles, was investigated to catalyze three- componet (A3) coupling reaction of aldehydes, alkynes and amines. It gave the corresponding propargylamines in good to excellent yields under the solvent-free condition and besides, CuI nanoparticles could be easily recovered and maintained activation in repetitious use.4. Research on the reaction of guanidinylation of aryl Iodides catalyzed by CuI NanoparticlesThis part gave a novel way to synthesize a series of substituted iodobenzene from aniline as the starting material based on the Sandmeyer Reaction and characterised the products with related spectroscopy datas. In addition, we studied the reaction of guanidinylation of aryl iodides catalyzed by CuI Nanoparticles which gave a good yield.

Related Dissertations

  1. Research on the Organic Reactions Catalyzed by Cu(Ⅱ),O621.251
  2. Research on the Aqueous Reactions Promoted by Diacetate Iodobenzene and the Sonogashira Coupling Reaction Catalyzed by Cu(Ⅱ)/Biimidazole,O621.251
  3. The Research on Palladium-Catalyzed Difunctionalization Reactions of Alkenes and Trifluoromethylation of Indoles Reactions,O643.32
  4. Study on Using Sepiolite As Supported Catalysts in Selective Hydrogenation of Cinnamaldehyde to Cinnamyl Alcohol,O643.32
  5. Study on the Synthesis of the Polypyrrole-Cobalt Oxides and Their Catalytic Behavior for the Electroreduction of H2O2,O643.32
  6. Study on Dehydration of tert-Butyl Alcohol Catalyzed by Functionalized Ionic Liquid,O643.32
  7. Studies on Selenium-Catalyzed Carbonylation to Unsymmetrical Ureas,O643.32
  8. New aza- carbene complexes immobilized palladium and catalytic chlorinated aromatic Suzuki coupling reaction,O643.32
  9. Phthalocyanine -based electron donor - acceptor assembly and performance of water photolysis,O643.32
  10. Palladium catalyzed guiding purine -purine C6- aryl ( nucleosides ) reaction of aryl,O643.32
  11. Epoxidation of olefins with high activity cobalt zeolite catalysts,O643.32
  12. Organic Hydrogen Phosphite or Hydrogen Phosphate Catalyed Friedel Crafts Amidoalkylation Reaction and Dinuclear Catalysts Applications in Asymmetric Reactions,O643.32
  13. Transition-Metal Catalyzed Carbon–Carbon Couplings,O643.32
  14. Research on Iron/Copper-cocatalyzed C-o, C-N Coupling Reaction and Copper-catalyzed Coupling Reaction of Terminal Alkyne,O643.32
  15. Ru-catalyzed Cross Couping Reaction Via C-H Activation Using Arylbronic Acids,O643.32
  16. The Design of Chial β-Amino Alcohols and their Application to the Asymmetric Henry Reaction and the Asymmetric Reduction of Prochiral Ketones,O643.32
  17. Novel Hydrogen Bond Promoted Organocatalytic Asymmetric Michael Reactions,O643.32
  18. Homogeneous Oxidation of Propane to Produce Peroxides,O643.32
  19. Palladium-catalyzed Synthesis of Endiynes Base on Bromoalkynylation of Alkynes,O643.32
  20. Study on Kinetics and Morphology of Calcium Carbonate Precipitation Catalyzed by Bacterial Carbonic Anhydrase,O643.32
  21. Aqueous solution of palladium-catalyzed Ullmann poor electrical coupling reaction of aromatic iodides,O643.32
  22. Nano- Pd catalytic oxidation of formic acid,O643.32

CLC: > Mathematical sciences and chemical > Chemistry > Physical Chemistry ( theoretical chemistry ),chemical physics > Chemical kinetics,catalysis > Catalytic > Catalytic reaction
© 2012 www.DissertationTopic.Net  Mobile