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The Study on the Distribution of Lung Cancer Associated Antigen Detected by Monoclonal Antibody N-35 in Serum.

Author: LuoXiang
Tutor: WangQinQin;ZhouKeMin
School: Kunming Medical College
Course: Oncology
Keywords: monoclonal antibody N-35 lung cancer associated antigen distribution serum
CLC: R734.2
Type: Master's thesis
Year: 2004
Downloads: 30
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Purpose.To study the difference and the significance of the distribution of lung cancer associated antigen in sera.Methods:By Western Blot method examining lung cancer associated antigen detected by monoclonal antibody N-35 in sera of fifity cases with malignant tumor , seventy-two cases who are healthy with two or three positive lung tumor markers, ninety-six cases who are healthy without positive lung tumor markers respectively.Results:The positve rate is 42%,2.77%,0% in the MTG,HGWLTM,HGNLTM respectively,There is statistical significance between MTG and HGWLTM,between MTG and HGNLTM(p < 0.01),not statistical significance between HGWLTM and HGNLTM(p > 0.05),the positive rate of lung cancer group is higher than the other malignant tumor group,but there is no statistical significane(p > 0.05) Conclusion:Lung cancer associated antigen detected by monoclonal antibody N-35 significantly exists in sera of malignant tumor cases,specially lung cancer cases,less exists in sera of health cases.

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CLC: > Medicine, health > Oncology > Respiratory system tumors > Lung tumors
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