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Influences on Skin Patch Test Reaction in Chinese Due to Loratadine in Conventional Dose

Author: LiPing
Tutor: ShiXin
School: Suzhou University
Course: Dermatology and Venereology
Keywords: loratadine patch test inhibitory effect
CLC: R758.2
Type: Master's thesis
Year: 2011
Downloads: 2
Quote: 0
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Abstract


Objective: The double-blind, controlled, randomized study to assess patch test reaction while under the effects of loratadine.Method: 121 patients with a positive patch test to nickel sulfate randomized divided into two groups, one group of 61 patients received loratadine 10 mg daily, and another group receive placebo daily during a 14-day period. The patch test was applied at day 11,and clinical evaluation of patch test was conducted at day 14. Intention to treat population was used in data analysis.Result: 55 patients in experimental group and 53 patients in control group showed positive reaction as before, and there was no significant difference in two groups.Conclusion: The inhibitory effect of loratadine in conventional dose on skin patch test reaction allergic to nickel sulfate is limited.

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CLC: > Medicine, health > Dermatology and Venereology > Dermatology > Allergic and toxic skin diseases
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