Dissertation > Excellent graduate degree dissertation topics show

Preparation and Characterization of Hybrid Nanoparticles by Miniemulsion Polymerization and Atom Transfer Radical Polymerization

Author: ZhangJianJun
Tutor: LiuFengZuo；LuYunFeng
School: Jilin University
Course: Polymer Chemistry and Physics
Keywords: Miniemulsion Atom transfer radical polymerization (ATRP ) ZnO MEH-PPV Fe3O4 BSA BP-RNase A Hybrid nanoparticles
CLC: TB383.1
Type: PhD thesis
Year: 2009
Downloads: 397
Quote: 0
Read: Download Dissertation

Abstract


In this paper, miniemulsion atom transfer radical polymerization technique zinc oxide / polystyrene (ZnO / PS), polyphenylene the ethylene / the polystyrene (MEH-PPV/PS), iron oxide - poly 2 - 2 methyl acrylate, ethyl (Fe3O4-PDMAEMA) and protein - poly 2 - dimethylamino ethyl acrylate (protein-PDMAEMA) hybrid nanoparticles. For the ZnO / PS hybrid nanoparticles modified comonomer MPS the modified adjustment of ZnO nano-particle surface hydrophobicity, two different structures of ZnO nanoparticles coated PS and PS coated ZnO nanoparticles hybrid particles. The hybrid particles not only retains the photoluminescence properties of ZnO with organic polymers flexibility, ease of processing, and has some potential applications in optical materials and optoelectronic devices. MEH-PPV adjusted miniemulsion system azobisisobutyronitrile (AIBN) initiator addition amount of the conjugate length to obtain a having a different emission wavelength MEH-PPV/PS fluorescent nanoparticles. Further adding a copolymerizable monomer acrylic acid (AA), we can get a surface with a carboxyl functional group of the P (S-co-AA) / MEH-PPV fluorescent nanoparticles. This high brightness, different light emitted fluorescent nanoparticles with a functional group has a good prospect of application in the field of optics and biology. Fe3O4 nanoparticles surface grafted water-soluble polymer PDMAEMA Fe3O4-PDMAEMA hybrid nanoparticles through in situ atom transfer radical polymerization method using methyl iodide PDMAEMA quaternized improve Fe3O4-PDMAEMA hybrid nano-particles in the surface charge and the dispersibility of the aqueous phase. Hybrid nanoparticles in the aqueous phase of the stable dispersion and with a positive charge can be used as a protein carrier, and the outer magnetic field under the action of the protein is carried into the human Hela cells, is a promising industrial catalytic and biological medical materials. -PDMAEMA and ribonuclease (BP-RNase A)-PDMAEMA hybrid nanoparticles of different sizes can be obtained by controlling the atom transfer radical polymerization time and the initiator of the degree of modification of bovine serum protein (BSA). Due to the presence of the PDMAEMA, the surface of the hybrid particles with a high positive charge, have a highly efficient cell membrane penetrating simultaneously linear PDMAEMA reduces the ribonucleic acid (RNA) BP-RNase A macromolecular substrate steric role in the BP-RNase A-PDMAEMA still has excellent apparent activity of hybrid nanoparticles. BP-RNase A surface PDMAEMA can resist within the RNase inhibitor Hela cells, it demonstrate efficient cytotoxic on Hela cells, which will make such a hybrid nanoparticles become a has potential applications in the biomedical field, The value of anti-cancer drugs.

Related Dissertations

  1. Study on the Chimisorption Removal of FCC Gasoline Sulfur Compound,TE624.55
  2. Synthesis and Characterization of High-performance Polyacrylonitrile,O631.3
  3. Electrochemical Studies on Interaction between ApoCopC、BSA and Cu(Ⅱ)、Cu(Ⅰ)、Cd(Ⅱ)、Ag(Ⅰ),O646
  4. Spectral and Electrochemical Research of Epirubicin Hydrochloride with Its Analytical Application,TQ465
  5. Cyclodextrin -modified magnetic nanoparticles synthesis and study drug carrier,TQ460.1
  6. Preparation of ZnO -based microemulsion photocatalytic material,O614.241
  7. Influence of Doping Effect on Zinc Oxide by First Principles Studies,O614.241
  8. Preparation of Functional Miktoarm Star-block Copolymers Via Combination of Lfrp and "Click Chemistry" Techniques,O631.3
  9. Fabrication, Defect Manipulation and Optical Properties of ZnO Hybrid Materials,TB33
  10. Organic/Inorganic Hybird Nanoparticles Modified Via Surface-Initiated Living Radical Polymerization,TB383.1
  11. Synthesis of Magnetic Fe3O4 Microparticles and SiO2/Fe3O4 Composite Spheres,TB383.1
  12. Preparation and Characterization of Multifunctional Fe3O4/ZnO/SiIO2 Nanocomposites,TB383.1
  13. Synthesis of Novel Ferrite Pigments and Its Application on Magnetic Inks,TQ622.15
  14. Design, synthesis and characterization of the star polymer,O631.3
  15. Hydrogen Evolution Process of Water Electrolysis Assisted by TiO2 Nanotubes and TiO2/ZnO Nanorodes Assembled on Ni Substrate,TQ116.21
  16. Synthesis of Uniform Magnetite Nanoparticles Via W/O Interface System Applied as Bio-Labels,TB383.1
  17. Thermosetting epoxy microsphere preparation, characterization and surface functionalization of,O631.3
  18. Fe 3 O 4 , carbon nanotubes and graphene reinforced regenerated cellulose membrane research,TB383.1
  19. Sol - gel method p -type ZnO films,O484.1
  20. Synthesis and Characterization of ZnO Films by Ultrasonic Spray Pyrolysis,TB43
  21. The Effect of Huangqichonglougushen on Expression of NF-ΚB in Membranous Nephropathy Rats,R285.5

CLC: > Industrial Technology > General industrial technology > Materials science and engineering > Special structural materials
© 2012 www.DissertationTopic.Net  Mobile