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Background and Purpose: Vibration Response Imaging (Vibration response imaging, VRI) the lungs breathing Imaging Diagnostic Systems is a new, dynamic lung imaging equipment using vibration response imaging technologies, through the acquisition of lung airflow vibration signal digital to analog conversion and electronic computer processing, after intrapulmonary sound processing, conversion to a dynamic image, identify the wet and dry rales, and able to calculate the percentage of the total lung energy of the lungs each region vibration energy. VRI pulmonary respiration Imaging Diagnostic Systems is a non-invasive way to check that no radiation damage, and the operation is simple, easy to grasp, operation by clinicians bedside. This inspection method has aroused extensive attention at home and abroad, the study involved a respiratory disease related research as well as cardiovascular disease such as heart failure, a number of studies have prompted the vibration response imaging system (Vibration response imaging system VRIXP) in healthy population stability, repeatability, high reliability interobserver; rales detection sensitivity, and specificity were good; chronic obstructive pulmonary disease (Chronic obstuctive pulmonary diseases, COPD) patients VRI image there are relatively specific performance. The VRI differences between the experimental study of chronic obstructive pulmonary disease patients and healthy controls, to provide a new basis for the clinical diagnosis of chronic obstructive pulmonary disease, and to study changes in the VRI scores before and after treatment of chronic obstructive pulmonary disease patients compared lung function and other indicators, to explore the Efficacy new VRI can become a chronic obstructive pulmonary disease. Materials and methods: Select from September 2010 to February 2011 a total of 40 patients with acute exacerbation of chronic obstructive pulmonary disease Check Henan Chest Hospital Respiratory Ward and 40 healthy volunteers, chronic obstructive pulmonary disease (COPD) group compliance guide to diagnosis and treatment of chronic obstructive pulmonary disease (2007) diagnostic criteria of COPD: pulmonary function prompts FEV1/FVC lt; 70% (Forced expiratory volume in one second / normal forced vital capacity, first second forced expiratory volume / forced vital capacity ratio), age 18-78 years old, no recent use of bronchodilators or elution. Healthy controls inclusion criteria: Age between 18-65 years of age, lung function 80% lt; FEV 1 pred% lt; 120% (Forced vital capacity FVC percentage of percentage of predicted value), 80% ≤ FVC ≤ 120% ( forced vital capacity, FVC) and FEV1/FVC gt; 75% (Forced expiratory volume in one second / normal forced vital capacity ratio of the first second forced expiratory volume / forced vital capacity). smoking, bronchodilator medications is not used in the near future, generally in good condition, without cardiopulmonary underlying disease. Exclusion criteria were: hirsutism, thorax, spinal deformity (such as: chicken breast, scoliosis), the pacemaker, the acquisition may affect lung sounds. Male COPD patients accounted for 31 cases, 9 females, average age 54.24 11.17 years, healthy people, 22 males and 18 females, mean age 41.46 ± 938 years. All COPD patients 10-18 days of treatment by anti-inflammatory, anti-asthma, chest tightness, asthma symptoms, general conditions improved again line the blood count, arterial blood gas analysis, pulmonary function, VRI check. Observation: the VRI image characteristics of healthy human the VRI image characteristics and COPD patients; auscultation rales with VRI rales monitoring relations; COPD patients treated before and after the VRI score difference and lung function changes. Describe COPD and healthy volunteers auscultation wet and dry rales the VRI image monitoring the relationship;, and both MEF (maximum energy diagram the Max energy frame), image development dynamic, image jump sense, EVP curve (acoustic signal, Envelope of Acoustic Signal ) differences; COPD patients before and after treatment MEF vibration curve, jumping flu differences. SPSS13.0 statistical analysis software package for data processing of measurement data to x ± s, non-normally distributed data using the arithmetic mean said. The groups were compared using t test, compared by χ2 test, P lt; 0.05 as statistically significant. Results: 1. The healthy volunteers vibration energy curve smooth continuous contains 3-4 cycles, within 12 seconds, the maximum vibration energy value between 1.5-3.5, each cycle of the inspiratory and expiratory phase composition, vibration energy Figure lungs at the same time, the dynamic image synchronization. The image does not jump, rare wet and dry rales. Maximum energy diagram basic defect, the edge is smooth and complete. Volunteers gender, age of the total evaluation of the VRI image (rales, abnormal number of curves, the sense of jumping morphological abnormalities, MEF) the results no impact (P gt; 0.05). 2 healthy volunteers auscultation were not found rales the VRI monitoring found three cases exist rales auscultation rales in line with the rate of 92.5%. 33 cases in patients with COPD auscultation rales VRI detection found in 29 cases there are rales, the compliance rate was 87.9%. In healthy volunteers and patients with COPD, VRI rales monitoring and auscultation overall compliance rate was 90.4%. 3.COPD the VRI image observed in patients with: rales appeared curve expiratory phase low-lying, image development occurs synchronization EVP (Envelope of Acoustic Signal) amplitude different, EVP dyssynchrony about MEF image area are not equal, MEF The percentage of missing COPD group was significantly higher than the healthy group was statistically significant between the two groups. VRI image 4.COPD patients before and after treatment evaluation (rales number of abnormal curve, a sense of jumping, morphological abnormalities MEF) compare the presence of a significant difference (P lt; 0.05) anomaly curve separately evaluate the difference was not significant (P gt; 0.05). VRI improve the value of the rate of improvement in FEV1 linear correlation r = -0.617 (P lt; 0.05). The regression equation Y = 0.067-0.156X (Y: FEV1 changes in the value of X: VRI image change scores). Conclusion: 1. The VRI checks of healthy people between the different age, gender was no significant difference, good stability, VRI check can be used as an objective index to evaluate lung function. 2. Consistency, in line with the requirements of clinical use in patients with COPD and healthy volunteers the VRI the rales monitoring and auscultation. COPD patients VRI results with normal people exist significant differences, can assist in the diagnosis of COPD. COPD patients treated before and after the VRI image evaluation exist significant differences, the VRI improve the value of FEV1 improvement rate there is a good correlation, and therefore can be considered as an indicator to judge the efficacy.
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