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The invasive behavior is a critical prognostic factor for gliomas and contributes to the failure of current therapeutic modalites. Despite immense advances in brain tumor therapy, including minimally invasive neurosurgery, neuronavigation system, gammatherapy and new chemotherapeutics, has been taken with the development of medical sciences and technology within past 10 years, high recurrence and absence of improved survival in gliomas have still been the major problem for neurosurgeons.On the other hand, various invasive phenotypes of intracranial non-glial tumors also have been found, such as invasive pituitary adenomas, meningiomas and malignant metastatic tumors. Although the invasive phenotypes of non-glial tumors have the capacity of invading into surrounding tissure and stucture, their invasion was much poorer and has much lower damage than gliomas. Surgical excision of non-glial tumors is usually associated with long-term survival or cure.The differences of invasion between cerebral gliomas and non-glial tumors highlight the necessity to comparative study on their invasive
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