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Analysis of Clinical Features and Relevant Risk Factors of Hypertension among Retired Cadres in Jilin Province

Author: LiuYuLian
Tutor: SunJie
School: Jilin University
Course: Clinical
Keywords: Elderly hypertension Clinical features Antihypertensive therapy Riskfactors
CLC: R544.1
Type: Master's thesis
Year: 2013
Downloads: 50
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Abstract


Epidemiological surveys showed that the prevalence of hypertensionincreased year by year, especially in the elderly. Hypertension is aprimary cause lead to morbidity and mortality, such as congestive heartfailure, stroke, coronary heart disease, renal failure, which would seriousimpact on the elderly’s life expectancy and quality of life. Thus, toexplore the clinical features of hypertension, and evaluate the therapeuticeffect is very important to guide to the next treatment. In this study,574retired subjects were collected from medical examination center in theFirst Hospital of Jilin University between2006and2010. Retrospectiveanalysis is used to explore the clinical features of hypertension andrelated risk factors in the elderly, and to evaluate the therapeutic effect.Providing a scientific basis for the development of targeted preventionand treatment strategies for hypertension in the elderly.Objective(1)To evaluate the prevalence of hypertension and its clinicalfeatures in our hospital of retired elderly cadres in the medicalexamination center;(2)To explore the relationships between hypertensionand blood glucose, blood lipids, obesity, fatty liver and other metabolic disorders among elderly people;(3)To selected risk factors patients withhypertension, and to provided evidence for further study of hypertensionamong the elderly.MethodsRetired subjects were randomly selected from Medical ExaminationCenter of the First Hospital of Jilin University. There are a total of574subjects,537males,37females, the average age is72.42±6.81.Retrospective analysis was used for the general population, bloodpressure levels, complications and drug use and other indicators in fiveyears, and analysis the clinical features and treatment of elderly patientswith hypertension.ResultsFrom2006-2010, the prevalence of hypertension in the elderlywere65.67%,65.87%,66.17%,66.56%,70.07%,the difference wassignificant compared the fifth year with the first year(P <0.05). Theelderly hypertension patients, awareness, treatment rates, control rateswere94.16%、44.83%、28.38%in the first year, the awareness, treatmentrates, control rates were98.02%、47.54%、27.58%in the fifth year, theycompared with each other were no statistically significant (P﹥0.05).Compared to61-70year-old group, the prevalence, awareness and treatment of hypertension was significantly higher in the elderly group(age>80years) in the fifth year (P <0.05). Systolic blood pressure anddiastolic blood pressure were growth with age in the elderly patients, andthe systolic blood pressure increased significantly between the fifth yearand the first year (P <0.05). Single anti-hypertension agents and multipleanti-hypertension agents could reduce blood pressure, multipleanti-hypertension therapy was more effective to control of blood pressurecompared to single anti-hypertension agents and blood pressure lessvolatile. The prevalence of coronary heart disease, diabetes, fatty liver,hyperlipidemia, obesity were12.20%,61.80%,25.80%,42.50%and45.60%, in2006, respectively; And in2010were12.20%、61.80%、25.80%、42.50%、45.60%, respectively. Compared with the first year,prevalence of coronary heart disease and fatty liver disease wasstatistically significant in the fifth year (P <0.05); The prevalence ofobesity and hyperlipidemia is presented to a descend trend as age rises,but only the hyperlipidemia was statistically significant between the firstyear and fifth year (P<0.001). In hypertension subjects, the prevalence ofdiabetes, fatty liver diseases, hyperlipidemia and obesity is higher thanthe non-hypertension subjects. For the urine protein and retinalarteriosclerosis abnormal rate, the fifth year was significantly higher thanthe first year (P <0.05). Logistic regression analysis showed that the riskfactors in elderly population with hypertension were age (1.08,95% CI:1.06-1.07), diabetes (1.55,95%CI:1.16-2.10), coronary heart disease(2.11,95%CI:2.03-2.65), hyperlipidemia (1.63,95%CI:1.40-1.89),obesity (2.22,95%CI:2.04-2.72), smoking (1.95,95%CI:1.55-2.45),sleeping (1.59,95%CI:1.28-1.32).Conclusions:1. In elderly subjects, the prevalence of hypertension was increasedwith age.2. Both systolic blood pressure and diastolic blood pressureincreased with age in elderly subjects, and systolic blood pressureincreased higher than diastolic blood pressure.3. The prevalence of coronary heart disease, diabetes, fatty liverincreased with age, the prevalence of hyperlipidemia and obesity reducewith age in elderly hypertension population. In hypertension subjects, theprevalence of coronary heart disease, diabetes, fatty liver diseases,hyperlipidemia and obesity is higher than the non-hypertension subjects.4. Elderly hypertension patients with abnormal rate of retinal arteryand urinary protein increased with age.5. For elderly hypertension subjects, the related factors included:age, diabetes, coronary heart disease, dyslipidemia, obesity, smoking,sleeping.

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CLC: > Medicine, health > Internal Medicine > Heart, blood vessels ( circulatory ) disease > Abnormal blood pressure > Hypertension
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