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The Retrospective Analysis of Clinical Data of Renal Tumors

Author: ChangDongQing
Tutor: WangQinZhang; DingGuoFu
School: Shihezi University
Course: Clinical
Keywords: Renal cell carcinoma Incidental Symptomatic Therapy Pathology Prognosis
CLC: R737.11
Type: Master's thesis
Year: 2013
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Abstract


Objective:1To study the clinical characteristics of renal cell carcinoma (RCC), such as diagnosis and treatment,enhance the understanding of RCC, objectively evaluate and conclude the treatment of RCC.2Study of Incidental Renal cell Carcinoma(IRC): clinical characteristics, treatment, pathologic type andprognosis factors, compared with that of people with Typical Renal cell Carcinoma (TRC).Methods:1Collected the clinical information of121renal cell carcinoma patients in our hospital between January2003to February2012, and retrospective analyses of the information.2Based on whether have typical clinical symptoms break up into incidental renal cell carcinoma (IRC)group and typical renal cell carcinoma (TRC) group, which of clinical characteristics were compared andanalysed.Results:1Collection of men and77cases in patients (63.64%), female44cases (36.2%), the male to female ratio isapproximately1.75:1, the average (57.06±11.66) years old,49cases of TRC (40.50%),70cases of IRC(59.50%). Main auxiliary examination is b-ultrasonic and CT examinations.99cases of Radicalnephrectomy (81.84%),20cases of partial nephrectomy (16.56%); General immune therapy after operationof103cases. Pathology results:97cases of clear cell renal cell carcinoma (80.17%),11cases of papillaryrenal cell carcinoma (9.09%),6cases of chromophobe renal cell carcinoma (4.96%), multilocular cysticrenal cell carcinoma and gene fusion type cancer, each had2cases (3.4%),3cases of mixed type cellcancer(2.48%). Follow-up patients to calculation median survival time of56.78after months,1year,3yearand5year survival rates are as follows:97.0%,84.0%,63.0%.2IRC accounted for this research was59.50%(72/121).There was no significant difference of gender, age,suffering from side kidney, time of surgery, bleeding volume of surgery, average hospital days aftersurgery between two groups (P>0.05).Compare IRC group which select Partial nephrectomy betweensymptoms group, the differences had statistics significance (P<0.05). Common tumor types in IRC groupwas97.22%, the tumor diameter (4.45±1.75) cm, clinical staging83.33%for T1, compared with the TRCgroup, differences are statistically significant (P<0.05). Median survival time for the IRC group69.57months,3and5-year survival rate for patients with88%and77%, TRC group median survival time is59.58months,3and5-year survival rate for patients with77%and56%, two group comparisonsdifferences are statistically significant (P<0.05).Conclusion:1With the development of medical imaging technology, a higher proportion of IRC and early RCC to seekmedical advice. Typical symptoms of RCC no longer necessary to diagnose a RCC. Ultrasound and CT forthe diagnosis of RCC is more important.The preferred way for early treatment of renal cell carcinomaradical resection for renal cell carcinoma, but gradually in nephron-sparing surgery surgery in clinicalapplication.2The majority of IRC had the characteristics of early RCC,. In our study, the effects of LRN surgery forIRC patients are satisfied, and prognosis was better. It is important to regular health examined for earlydiagnosis, treatment and prognosis of RCC.

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CLC: > Medicine, health > Oncology > Genitourinary tumors > Urinary tumors > Kidney,renal pelvis tumor
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