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Objective:By applying benefit spleen kidney is given priority to evidence-based medicine in TCM diagnosis and treatment plan clinical observation the clinical effect of the treatment of chronic nephritis albuminuria, the ultimate goal of CGN patients24hours urine protein quantitative control the during the study period, on average, lower than the baseline by more than50%, keep the stability and improve renal funct i on.Methods:52patients met the inclusion criteria of patients with primary glomerular disease (CKD1-2), using randomized controlled methods, case will be qualified in accordance with the ratio3:1were divided into treatment group (treatment group was given treatment with syndrome differentiation of traditional Chinese medicine treatment group),39cases and the control group based in treatment group (ARB)13cases for clinical observation. Treatment group to jiangyin day jiang Chinese medicine medicinal broth, a dose, points in the morning and evening clothes; Control group50mg/day of chlorine to sand jotham nail. Observation time is6months.24hour urinary protein before and after treatment were observed quantitatively, serum creatinine, blood urea nitrogen, glomerular filtration rate and the change of TCM syndrome integral, and the obtained data were compared between group and group, for the statistical analysis using SPSS13.0software.Results:1. The treatment group the total effective rate was87.17%, control group total effective rate was61.32%, treatment group curative effect is better than that of control group (P<0.05)2. The treatment group and control group before and after treatment for24hours urine protein quantitative comparison in the group, had significant difference (P<0.05), treatment group and control group after treatment,24hours urinary protein quantitative comparison between groups, statistically significant difference (P<0.05)3. The treatment group and control group after treatment by TCM syndrome curative effect standard evaluation, the total effective rate were90.87%and66.92%respectively, the difference has statistical significance (P<0.05).Conclusion:Benefit mainly spleen and kidney syndrome differentiation treatment can significantly reduce chronic glomerular nephritis patients24hours urine protein quantitatively, the comprehensive efficacy and disease syndromes curative effect is superior to the control group.
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