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Study on Bacteri Status in Conjunctival Sac with Ocular Surface Burns

Author: GuoZuo
Tutor: ZhouShanZuo
School: Chongqing Medical University
Course: Ophthalmology
Keywords: ocular surface burns conjunctival sac germiculture drugsensitivity test
CLC: R779.1
Type: Master's thesis
Year: 2013
Downloads: 1
Quote: 0
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Abstract


ObjectiveTo understand the bacteria status in the conjunctival sac with ocularsurface burns, for the treatment of infection and aseptic preparation beforeoperation.MethodsA total of26eyes with ocular surface burns in our hospital wereexamined,and another25normal eyes in the same crowd were analyzed asthe control group. Then, the results of bacterial culture results and drugsensitivity test were analyzd.ResultsThe positive rate of the cultivation was53.85%(14/26) in ocular surfaceburns eyes,and56%(14/25) in normal eyes. There was no statisticaldifference between two groups(χ~2=0.024,P=0.877). In two groups ofconjunctival sac,5species bacteria were cultivated, Gram—positivebacteria in13eyes(92.86%), Gram—negative bacteria in1eyes(7.14%).There were9Staphylococcus epidermidis strains (64.29%)and Staphylococcus capitis2strains (14.29%) in burn eyes group. Incontrol group, there were6Staphylococcus epidermidis strains (42.86%),5strains of Staphylococcus haemolyticus (35.74%).2groups of conjunctivalsac advantage strains were mainly Staphylococcus epidermidis.The positive rate of burn eyes of Staphylococcus epidermidis was42.86%. It was lowerthan the normal group(64.29%). There was no statistical diference ofpositive rate between two groups(P=0.449). The positive rate of burn eyesof Staphylococcus haemolyticus was significantly higher than that innormal eyes. There was statistical diference of positive rate between twogroups(P=0.041). Conjunctival bacteria (coagulase negativeStaphylococcus) in burn eyes group resistant to the commonly used inclinical drug, such as penicillin, ciprofloxacin,erythromycin; sensitive tomoxifloxacin, gentamicin.ConclusionThere is no influence whether or not with ocular surface burns inbacterial positive rate, the number of bacterial species, the constituent ratioof Gram classification and dominant strain. Compared with the normal eyes,the positive rate of burn of conjunctival sac hemolytic Staphylococcus wasincreased. The bacterial culture of conjunctiva sac is necessary fortreatment of ocular surface burns patients. And sensitive antibiotics shouldbe used to prevent eye infections.

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CLC: > Medicine, health > Ophthalmology > Eye injury with foreign body
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