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Objective: Investigation of the relationship between type 2 diabetic peripheral neuropathy’s data and TCM blood stasis syndrome in order to make it as theoretical reference for clinical analyzing and differentiating and therapy of DPN.Method: Based on diagnosis standard in WHO Diabetes Mellitus diagnosis standard, according to analyzing and differentiating standard in“New Clinical Research Guideline Of Traditional Chinese Medicine”published in 2002,“Guidebook of prevention and cure of DM with Traditional Chinese Medicine”published in 2007, we analysis and divide 148 patients with DPN into 5 groups, they are blood stasis obstructing the collaterals, extreme heat due to deficiency of yin, dampness and heat block spleen, deficiency of both qi and yin, deficiency of both yin and yang. Record their index such as: sex, age, blood pressure, course of disease, fasting blood-glucose (FBG), HbA1C, blood-fat, ET-1, PAI-1, NO. Analysis the data of above 5 groups with Statistics method, we give marks under clinical symptoms of blood stasis obstructing the collaterals group patients, analyzes the correlativity of blood stasis syndrome integration and their index. Result:Blood stasis syndrome integration of DPN is irrelevant with FPG, HDL-C, but it is positive correlation with HbA1c, TG, TC, LDL-C, ET-1, PAI-1; and it is negative correlation with NO.Conclusion:1. Blood stasis syndrome is the key of DPN’s case conversion. we can place ET-1, PAI-1, NO as reference index of DPN blood stasis obstructing the collaterals syndrome.2. Differences in aspect of blood-fat of DPN blood stasis obstructing the collaterals type. Outcome: we can place TG, TC, LDL-C as reference index of DPN blood stasis disease. Benefiting vital energy, invigorating the circulation of blood should be the guideline for treatment.
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