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Preparation and properties of biodegradable polycarbonate
Author: WangJiaLi
Tutor: LiuSuQin
School: Central South University
Course: Applied Chemistry
Keywords: Aliphatic polycarbonate Carbon dioxide Biodegradable Pyrolysis kinetics
CLC: TQ323.41
Type: Master's thesis
Year: 2010
Downloads: 205
Quote: 0
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Abstract
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Biodegradable polymer material polycarbonate decomposition products because of its good biocompatibility and non-polluting and has a wide range of applications , especially in the very promising medical materials and engineering plastics . As a synthesis of polycarbonate , carbon dioxide has important guiding significance for the use of renewable resources and green polymer field opened up . Paper first by anionic coordination polymerization reaction with the carbon dioxide (CO2) and ethylene oxide (PO) copolymer as a basic skeleton , the introduction of the third monomer is lactic acid unit ( LA ) , successfully obtained a novel structure of the bio- degradation random copolymer PPC-LA-PPO-LA, and by infrared spectroscopy , nuclear magnetic resonance spectroscopy , wide angle X- diffraction spectroscopy and elemental analysis characterization methods to determine the structure of the segments on copolymerization mechanism is also discussed . Article taking into account the influence of lactic acid unit content on the properties of the polymer . The results show that , with the LA content increased , the copolymer degradation of performance improvement . LA content of 9.35% , the first 10 weeks in a simulated human body fluid environment of weightlessness rate of 23% , a significant improvement in the in vitro degradation than LA unit before embedding . Molecular weight curve of the degradation process of the initial , surface dissolution dominant . Paper design and introduces a new method of calculating the nonlinear reduction method , and the aliphatic polycarbonate PPC - la - PPO- LA ( poly [ ( propylene -co- lactic acid) ester] carbonate ) pyrolysis power school study . The new calculation method is simple , scientific and rational thinking , and the apparent activation energy value of each conversion rate average relative error is less than 6.5% . The entire process of decomposition , the apparent activation energy value is 66.6-140.3 kJ · mol-1 , indicating that the corresponding multi-step reaction process and reaction mechanism of function between . (W / O) / W complex phase emulsion prepared PPC-LA-PPO-LA contained bovine serum albumin microspheres , and to examine the relationship between drug loading capabilities with external phase dispersant concentration . The preliminary analysis shows that , due to the the polymer residues tiny impurities , resulting in a drug-loaded microspheres prepared too low drug loading and encapsulation efficiency .
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CLC: > Industrial Technology > Chemical Industry > Synthetic resins and plastics industry > Polycondensation resin and plastic > Polyester resins and plastic materials > Unsaturated polyester
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