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The Parmocognosy and Chemical Composition Study of TaiBaiMi

Author: PengLiang
Tutor: HuBenXiang
School: Shaanxi College of Traditional Chinese Medicine
Course: Of Pharmacy
Keywords: Taibaimi Pharmacognosy Extraction and separation Organic acids
CLC: R284
Type: Master's thesis
Year: 2010
Downloads: 33
Quote: 1
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Abstract


Taibaimi aslo name as Notholirion,derived from the little bulb of Notholirionbulbuliferum (Lingelish.) Stearn. ,is one of the valuable Traditional Chinease Medicines (TCM) that has a long medical history. Taibaimi mainly grown in theprovinces of Shannxi,Xizhang,Sichuan and Yunnan. Taibaimi is walm in nature and little bitter in taste;has effect of relaxing the chest,invigorating stomach and analgesic. For treatment of stagnation of vital energy and epigastragia; distension and ache of stomach and abdominal;vomit;cough of wind-cold.Moreover,Taibaimi has pharmacolo-gical effect of antitumor,pain-alleviating[1-7].The thesis has made comprehensive pharmacognosy characteristics and chemical composition study of Notholirion hyacinthinum ( wils.)stapf .which come from Lilium Liliaceae Notholirion, and make a review of organic acid compounds.The issue through the methods of eye and microscopic observation,p-hotography and drawing combining,we have determined it’s pharmacogon-osy by making a comprehedsive study of original plant morpgology of Taibaimi and it’s organizations and powder characteristics,medicinal traits.Through this study we provided basis for its properties and micoscopic identification.Acorrding to the Phramacopoeia methods of water、ash and extact determination,we have set the content standards of Taibaimi’s water, total ash, acid insoluble ash and extacts.Using the system solvent extraction, TLC, silica gel column chromatography, LH-20 column separation to make systematically study of chemical constituents of Taibaimi,isolated five pure compounds(1,2,3,4,5) from Taibaimi.We cocluded the five compounds structure by using chemical identification and spectrometric determination (MS, 1H-NMR, 13C-NMR),identified compound 1 asβ-sitosterol(β-sitosterol);Compound 2 daucosterol(daucosterol);compound 3,4,5 are the organic acids, respectely:p-methoxy cinnamic acid (2-Propenoic acid,3-(4-methoxyphenyl)),hydroxy cinnamic acid (2-Propenoic acid,3-(4-hydroxyphenyl)),hydroxy cinnamid acid ester glucoside (β-D-Glucopyranose, 1-[3-(4-hydroxyphe-nyl)-2-propenoatel.

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