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TPM is obtained by the protein enzymatic pathway and a series of separation and purification means , of a new derived from zein antioxidant peptide . This article we focus on the TPM in oxidative stress and heat stress conditions significantly extend the life of C. elegans . Oxidative stress conditions , the TPM can extend the life of up to 27.6% of the C. elegans ; under heat stress conditions , the TPM can extend the life of the C. elegans 36.9% . Further studies have shown that , TPM reason why environmental stressors can significantly the ground extend C. elegans life because it shows a strong free radical scavenging ability , both in vitro and in vivo ; TPM can also increase superoxide dismutase SOD - 3 and heat shock protein HSP - 16.2 , that are resistant to stress-related protein expression and reduce the nematode body fat accumulation . Quantitative PCR results showed that TPM can also adjust some anti-aging gene expression , such as daf - 2 , daf - 16 , SOD - 3 , hsp - 16.2 , SKN- 1 , ctl - 1 , ctl - 2 and so on . These experimental results show that corn peptide monomers TPM through a variety of ways to improve the C. elegans resistance to environmental stress and prolong its life , is a natural anti-aging ingredients with great potential .
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