Dissertation > Excellent graduate degree dissertation topics show

The Observation of Age-related Macular Degeneration by Optical Coherence Tomography and Visual Electrophysiological Examination

Author: LinLin
Tutor: XuGuoXing
School: Fujian Medical
Course: Ophthalmology
Keywords: Age-related Macular Degeneration Optical Coherence Tomography Visual electrophysiological examination
CLC: R774.5
Type: Master's thesis
Year: 2011
Downloads: 55
Quote: 0
Read: Download Dissertation

Abstract


Purpose:To investigate the relationship betweenoptical coherence tomography (OCT)and visual electrophysiological examination of the macular region in age-related macular degeneration (ARMD).Method:OCT which measuring the thickness of nerves on the retina of Lesions vary from macular fovea and visual electrophysiological examination,including electroretinograms (ERG) and pattern visual evoked potentials (P-VEP),were used to measure 26 patients (31 eyes) with non-exudative age related macular degeneration and 27 patients (31 eyes)with exudative age related macular degenerationd who had been diagnosed with fundus fluorescein angiography (FFA).Twenty-one healthy volunteers(30 normal eyes)were also included in the study.Results:①The thickness of Retinal Neurepithelium Layer:group.The difference between the exudative group and normal group had statistically significant (P<0.01) . There was no significant difference in the thickness of the retinal neurepithelium layer between the non-exudative group and normal group (P>0.05).②Best-corrected Visual Acuity: Compared to the normal group,the best-corrected visual acuity of non-exudative group and exudative group were all significantly Reduced(P<0.01).The best-corrected visual acuity of exudative group were reduced more noticeably than non-exudative group(P<0.01)。③Dark adaptation ERG: Compared to the normal group,the amplitudes of the a and b waves in the non-exudative group were all significantly smaller ,and the peak times of the b waves were significantly lengthened(P<0.01)。Compared to the normal group,the amplitudes of the a and b waves in the exudative group were all significantly smaller ,and the peak times of the a and b waves were significantly lengthened(P<0.01)。Compared to the non-exudative group,the amplitudes of the b waves in the exudative group were all significantly smaller(P<0.05),and the peak times of the a and b waves were significantly lengthened(P<0.01)。④P-VEP:Compared to the normal group,the amplitudes of the P1O0 waves in both the non-exudative group and the exudative group were all significantly smaller(P<0.05),and the peak times of the P1O0 waves were significantly lengthened(P<0.01)。Compared to the non-exudative group,the amplitudes of the P1O0 waves in the exudative group were all significantly smaller(P<0.05),and the peak times of the P1O0 waves were significantly lengthened(P<0.01)。Conclusion:Changes of macular region and view function in the exudative group are more serious compared to the non-exudative group. These results also show that the damage to visual function is earlier than the change in the thickness of the retinal neurepithelium in the macular region in 31 early non-exudative eyes.The combination of OCT and visual electrophysiological examination is helpful to the diagnosis and early detection of ARMD who is not available for fundus fluorescence angiographic。

Related Dissertations

  1. High-resolution optical tomographic imaging study biological samples based on audience optical coherence tomography,Q6-33
  2. The Character of Retinitis Pigmentosa in Optical Coherence Tomography,R774.1
  3. The Application of Anterior Segment Optical Coherence Tomography in Evaluating the Morphology and Function of Filtering Blebs after Trabeculectomy,R779.6
  4. Based on frequency domain optical coherence tomography of human skin -resolution optical tomographic imaging studies,TP391.41
  5. Central Retinal Sensitivity after Intravitrea Injection of Bevacizumab for Fundus Neovascularization,R774.1
  6. Frequency domain optical coherence tomography imaging characteristics analysis and experimental study,TN27
  7. Analysis of Factors Related to Age-related Macular Degeneration,R774.5
  8. The Clinical Researches of Chinese Medicine about the Prescription of Reinforcing the Spleen to Turn Muddy Toward the Disease of Wet Age-Related Macular Degeneration,R276.7
  9. Measured by OCT primary acute angle-closure glaucoma retinal nerve fiber layer thickness preliminary study,R775.2
  10. Mild, moderate non- proliferative diabetic retinopathy study laser treatment of macular edema,R779.63
  11. Overall optical coherence tomography study of the key technologies,TN27
  12. Clinical Research on the Treatment of AMD Patients with Spleen Deficiency Dampess Ride Type by Shenling Baizhu Storm,R276.7
  13. Observe Two Types of Laser Photocoagulation Compare the Treatment of Diabetic Macular Edema Rencent Clinical Effect,R779.63
  14. Line imaging spectrometer based on frequency domain OCT studies focusing,TN27
  15. Study on the Controlling System for Optical Coherence Tomography Based on LabVIEW and the Signal Processing,TN911.7
  16. High myopia foveal retinoschisis secondary analysis of related factors,R778.11
  17. Intravitreal Bevacizumab Versus Verteporfin Photodynamic Therapy in Choroidal Neovascularization Due to Age-Related Macular Degeneration: A Systematic Review,R774.5
  18. Diabetic retinopathy and peripheral blood progenitor cell research and the relationship between diabetic retinopathy study nerve fiber layer thickness,R774.1
  19. Study of Diabetic Macular Edema Classification and Multifocal Electroretinogram Changes,R774.1
  20. The Research of the Relationship Between C Reactive Protein and Folic Acid and Homocysteine and Age Related Macular Degeneration,R774.5

CLC: > Medicine, health > Ophthalmology > Retina and optic nerve diseases > Macula,the central fossa disease
© 2012 www.DissertationTopic.Net  Mobile