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Meta-Analysis of the Effects to IVF about Salpingectomies

Author: ChenBing
Tutor: ZhengZhiQun
School: Fujian Medical
Course: Obstetrics and Gynaecology
Keywords: IVF-ET tubal pregancy salpingectomy meta-analysis
CLC: R713
Type: Master's thesis
Year: 2011
Downloads: 90
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Abstract


【objective】:To compare the pregnancy rates differences of patients have salpinges ,severe tubal dieases performed salpingectomy or not before IVF-ET in salpingian infertility curing.【method】: A systemic-through search of the literatures were performed of both prospective and retrospective studies , taking up the data for meta-analysis fowlled.【result】: 1. 5studies were included in the meta-analysis.2. This system evaluation is about whether infertility patients by tubal factors before IVF-ET must have salapingectomy or not, aims to compare the percent of clinical pregnancy and the ongoning pregnancy in this two groups.It takes five studies in this article,the nmbers of salpingectomy patients is 183,and the other group is 117.The result of comparation of the clinical pregnancy is (that) OR=1.56(95%CI,1.13-2.15)>1,the rhombus of the gram 1 is at the RT of the vertical line, that means the curation groups take better effectiveness. The result of comparation of the ongoing pregnancy is (that) OR=1.68(95%CI,2.20-2.36)>1,the rhombus of the gram 2 is at the RT of the vertical line,that means the curation groups take better effectiveness too.The result of comparation of the ectopic pregnancy is (that) OR=0.84(95%CI,0.4-1.75),the rhombus of the gram 3 is get across of the vertical line,that means no difference in two groups. The result of comparation of the embry transfer is (that) OR=1.5(95%CI,1.03-2.2)>1 the rhombus of gram 4 at the RT of the vertical line,that means the curation groups take better effectiveness too. From table7 we can see :Tubal factor infertility without salpingx if choice salpingectomy will influences ovarian function.Th e reason may be that operation impaired ovarian blood flow.Compare the retrieved oocytes between the salpingectomy group and the remaining group ,the p is <0.5: Salpingectomy will influences ovarian function and make the lower percent of the retrieved oocytes.【conclusion】: The infertility patients by tubal factors make the choice to IVF-ET,before IVF-ET taking some operation or not must detimine by the Patients’condition.In this meta-analysis we can find: The presence of hydrosalpinges in women considering IVF treatment is an indication for surgical treatment,it must be careful to do salpingectomy for that may cause lower response to stimulus of the ovarian.If the tubal have chance to choice salpingplasty then do that.If the disease is serious ,choice the surgery to cut the tubal but keep the blood vessel may be good ,but that need more RCT articles to proof.

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CLC: > Medicine, health > Obstetrics and Gynaecology > Gynecological surgery
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