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Background Coronary heart disease is one of the major diseases that endanger human health, coronary heart disease morbidity and mortality gradually increased with the improvement of people's living standards and lifestyle changes. After percutaneous coronary intervention (percutaneous coronary intervention, PCI) has become the preferred way of coronary heart disease treatment. Postoperative reconstruction of restenosis, to improve the quality of life in patients with less satisfaction problems Western medicine has yet to be completely resolved. Chinese medicine through the multi-target, multi-channel role, play a preventive role in restenosis and improve symptoms. Present, the the many Integrative workers this large number of basic and clinical research, in order to explore the effect of the Integrative Medicine, but in strict accordance with the principles of clinical research design random, double-blind, placebo-controlled clinical studies less . Objective To observe the drug test has role of Yiqihuoxue phlegm qi deficiency and phlegm stasis type of coronary heart disease after PCI patients quality of life, cardiac function, explore Integrative intervention in the long-term treatment of patients with coronary heart disease after PCI effect. Methods A randomized, double-blind, placebo-controlled, included in the September 2008 to December 2009, the Guangdong Provincial Hospital Heart Center, First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine Cardiovascular Division 121 cases of coronary heart disease after PCI meets standard cases observed, were randomly divided into experimental group (conventional Western medicine treatment of experimental drug) and the control group (placebo 10 conventional Western medicine treatment), respectively, before treatment, after treatment, 90 days and 180 days after treatment completed the Seattle Angina Scale ( seattle angina questionnaire, SAQ), coronary heart disease Integrative Quality of Life Scale NYHA cardiac function classification evaluation before treatment, after treatment, 180 days to complete echocardiography LVEF Determination, while observing the test drug safety and adverse reactions The resultant data entered into the computer using SPSS17.0 software for statistical analysis. Results in SAQ aspects, the test group and the control group at 90 days after treatment, 180 days in both scoring and total scores of each dimension improved significantly, and the difference was statistically significant (P lt; 0.05) difference between groups was not statistically significance (P gt; 0.05), but the experimental group compared with the control somatic degree of activity limitation, angina steady state, angina pectoris, treatment satisfaction dimension scoring group tended to increase. Integrative Quality of Life Scale in patients with coronary heart disease, the test group and the control group at 90 days after treatment, 180 days, scoring on in various dimensions and total scores were significantly improved, the difference had statistical significance (P lt; 0.05 ), between the two groups showed no significant difference (P gt; 0.05), but the test group than in the control group, there is an increasing tendency in the mental health, social dimension scoring. In LVEF, NYHA cardiac function classification, the treatment group, LVEF and NYHA class than before significant improvement (P lt; 0.05), the control group before and after treatment, the difference had no statistical significance (P gt; 0.05), treatment The difference between the latter group was statistically significant (P lt; 0.05). Conclusion Integrative treatment improvement in patients with coronary heart disease after PCI trend of the quality of life of a number of dimensions; and conventional Western medicine-based therapy plus trial medication Yiqihuoxue phlegm role marked improvement in coronary heart disease after PCI in patients with heart function role.
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