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META Analysis of Percutaneous Balloon Pulmonic Valvuloplasty and Surgery in Pulmonary Stenosis

Author: XieJingZuo
Tutor: TianJie
School: Chongqing Medical University
Course: Pediatrics
Keywords: Pulmonary valve stenosis Pulmonary valve percutaneous balloon angioplasty Surgery Meta-analysis
CLC: R726.5
Type: Master's thesis
Year: 2011
Downloads: 23
Quote: 0
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Abstract


Objective: Pulmonary valve stenosis is a relatively common congenital heart disease. Percutaneous balloon pulmonary valvuloplasty (PBPV) and surgical cure. In this study, the control experiments for PBPV and surgical treatment of pulmonary valve stenosis Meta-analysis to evaluate the efficacy and safety of PBPV with traditional surgery, from the point of view of evidence-based medicine, and to provide a basis for optimizing clinical treatment. : Retrieval PubMed, OVID, Medline, Chinese Biomedical Literature Database (CBMdisc), Chinese Science and Technology journals database, knowledge service platform. Pool of knowledge resources (CNKI), collect all pulmonary valve stenosis PBPV and surgical treatment controlled trial cases. Development of literature the inclusion and exclusion criteria, by two researchers independently screened literature quality assessment standards recommended by Shekelle literature, literature that met the inclusion criteria. Patients with baseline levels, such as age, weight, preoperative pulmonary valve value, compare the length of hospital stay and costs; surgical success rate, postoperative survival, the immediate postoperative PG values, pulmonary regurgitation MTPG (PG) The incidence of tricuspid regurgitation incidence, the last postoperative follow-up the PG value and the incidence of complications using the Revman software (version 5.0) Meta-analysis. Count data using relative risk (RR) and its 95% CI, percentage; measurement data using the mean difference (MD) and its 95% CI, compare the mean ± standard deviation (x ˉ ± s). Results: A total five, including three Chinese literature, foreign language literature 2, a total of 523 cases of pulmonary valve stenosis, are single-center, non-randomized study (IIa). The the PBPV group with the surgical group age, body weight, no statistically significant differences in preoperative the PG value and cost, PBPV group hospitalization time is shorter than the surgery group. Meta-analysis showed: no statistically significant differences in treatment success rate (96.2% vs 100%, P = 0.46); postoperative survival rate was 100%; two groups immediately after PG value was no significant difference ([20.96 ± 14.92) mmHg vs (18.24 ± 11.24) mmHg, P = 0.08]; PBPV postoperative pulmonary regurgitation incidence is lower than the surgical group (35.4% vs 71.1%, P = 0.007); PBPV group surgery after tricuspid regurgitation incidence is lower than the surgical group (9.24% vs 23.6%, P = 0.01); follow-up two sets of PG value of the difference was not statistically significant [(17.94 ± 14.08) mmHg vs (13.90 ± 9.82) mmHg, P = 0.11]; no statistically significant difference in the incidence of the two sets of complications (11.4% vs 28.3%, P = 0.14). Conclusion: PBPV and surgical treatment of pulmonary valve stenosis are safe and feasible treatment effect is similar, but each has its own advantages and disadvantages. PBPV treatment of pulmonary valve stenosis trauma, rapid postoperative recovery, fewer complications, but the treatment of selective; through strict indications, specifications, and skilled operation, the success rate can be further improved. Surgical treatment of pulmonary valve stenosis high success rate to adapt to a wide range, but a higher incidence of complications. PBPV to have surgery unsurpassed advantage, priority to select PBPV treatment of the indications pulmonary valve stenosis.

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CLC: > Medicine, health > Pediatrics > Pediatric surgery > Surgery in children of all physiological systems
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