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The Analysis of the Condition of Application of Carboprost Tromethamine in Cesarean Section of Central Placenta Previa

Author: ZhangJianQing
Tutor: SunJiangChuan
School: Chongqing Medical University
Course: Obstetrics and Gynaecology
Keywords: Tromethamine of Carboprost , Postpartum hemorrhage Central placenta previa Adverse reactions Prevention applications
CLC: R719.8
Type: Master's thesis
Year: 2011
Downloads: 19
Quote: 1
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Abstract


Objective: 1. Observed carboprost tromethamine used to prevent and reduce the effect of blood loss in the central placenta previa cesarean section. 2. Explore carboprost tromethamine central placenta previa cesarean section to prevent the timing of the application. Methods: The first part collected in our hospital from September 2002 to September 2007, indications of cesarean section and intraoperative diagnosis of 62 cases of central placenta previa, injection drug fetus harem body randomly divided into Carboprost ammonia butanetriol oxytocin group (30 cases) and oxytocin group (32 cases), compare their efforts to prevent and reduce the effect of blood loss and adverse reactions. The second part of our hospital from October 2007 to October 2010 cesarean testify intraoperative diagnosis of central placenta previa 54 patients were randomly divided into the conventional prevention group and actively prevent group, on the amount of bleeding, The incidence of postpartum hemorrhage, uterine sliver situation, blood transfusion and postoperative uterine involution were analyzed. Results: The first part Carboprost tromethamine blood loss (347.9 ± 187.0) ml significantly less than the oxytocin group (470.0 ± 347.4) ml (p = 0.03); at the same time, 24-hour total amount of bleeding carboprost tromethamine oxytocin group (410.4 ml ± 168.7) ml less than the reduction of oxytocin group (743.5 ± 557.4) ml (p = 0.01). Carboprost tromethamine groups were compared to the incidence of side effects such as nausea, vomiting, chest tightness, and facial flushing with oxytocin group difference was not significant (P gt; 0.05). Proactive prevention group in the second part of the blood loss (287.9 ??± 197.0) ml was significantly less than conventional prevention group (450.0 ± 327.4) ml (p = 0.03); same time, the total amount of bleeding for 24 hours active prevention group (325.4 ml ± 148.7) ml less than conventional prevention group (633.5 ± 657.1) m (lp = 0.01). The incidence of postpartum hemorrhage (χ2 = 4.5, p = 0.03), the utilization rate of uterine gauze (χ2 = 4.5, p = 0.035), and intraoperative and postoperative blood transfusion (χ2 = 6.27, p = 0.012) were significantly reduced. The uterine recovery of the active treatment group was significantly better than conventional prevention group (p = 0.04). However, the duration of hospitalization was no significant difference (p gt; 0.05). Conclusion: carboprost tromethamine can effectively reduce the amount of bleeding in the central placenta previa cesarean section. The positive prevention group than in the routine prevention group to reduce the amount of intraoperative and postoperative bleeding, reduce the occurrence of postpartum hemorrhage, uterine gauze and blood transfusion, promoting postoperative uterine involution effect more. In addition, when used should also be clear whether contraindications, and pay attention to the occurrence of adverse reactions.

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CLC: > Medicine, health > Obstetrics and Gynaecology > Obstetric surgery > Laparotomy
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