|
Objective: Detect the pathogenic microorganisms of vaginal and cervical secretions and microbial sensitivity test of mycoplasma, for understanding the female lower genital tract infection pathogens and mycoplasma species susceptibility, providing the evidence of clinical diagnosis and treatment.Methods: 13,857 cases of out-patients from Second Affiliated Hospital of Chongqing Medical University, collection of vaginal secretions, vaginal secretions check cleanliness, pH, amount of Lactobacillus, trichomonas, candida, clue cells. We collect cervical secretions of which 2378 cases of women, and culture mycoplasma, and do microbial sensitivity test of positive mycoplasma samples.Results: 1. 13,857 cases of patients, the occurrence of 5105 cases of lower genital tract infection (36.84%), which vulvovaginal candidiasis 1940 cases (14.00%), bacterial vaginosis 1886 cases (13.61%), trichomonas vaginitis 221 patients (1.59%), mycoplasma infection in 1058 cases (7.64 %), mixed infection 111 cases (0.80%), including vulvovaginal candidiasis with bacterial vaginosis 87 cases (0.63%), bacterial vaginosis is combined with trichomonas infection 22 cases (0.16%), trichomonas vaginitis with vulva merger vaginal candidiasis 2 cases.2. Mycoplasma infection in lower genital tract infection in 1058 cases (7.64%), ureaplasma urealyticum is the main mycoplasma (885/1058, 83.65%), followed by the merger of ureaplasma urealyticum with mycoplasma hominis infection (152/1058, 14.37%), the lowest infection rate is mycoplasma hominis (21 / 1058,1.98%).3. The microbial sensitivity test showed that ureaplasma urealyticum on the rate of high-sensitive drugs: doxycycline (832/885, 94.01%), minocycline (812/885, 91.75%) and clarithromycin (735/885, 83.05%), resistance is the high rate of sparfloxacin (813/885, 91.86%), ofloxacin (798/885, 90.17%) and L-oxyfluoride (683/885, 77.18%); on the ureaplasma urealyticum combined with mycoplasma hominis infection was higher in the minocycline (98/152, 64.47%), doxycycline (95/152, 62.50%) and josamycin (73/152, 48.03%), resistant medicine is the high rate of sparfloxacin (149/152, 98.02%), ofloxacin (146/152, 96.05%), L oxyfluoride (146/152, 96.05%) and azithromycin (146/152, 96.05%); of Mycoplasma hominis is sensitive to higher rates of minocycline (21/21, 100.00%), josamycin (21/21, 100.00%) and doxycycline (21/21, 100.00%), high rates of drug resistance azithromycin (21/21, 100.00%), clarithromycin (21/21, 100.00%) and erythromycin (21/21, 100.00%).Conclusion:The patients in our outpatient department are various types of lower genital tract infection, which vulvovaginal candidiasis and bacterial vaginosis are based, multi-pathogen infection accounts for a certain percentage. For the lower genital tract infection is a human public health problem, it must be attached importance. Ureaplasma urealyticum is the main infection of mycoplasma, and the microbial sensitivity test showed high resistance to quinolones. At the same time of treatment of mycoplasma infection, we should be combined with microbial sensitivity test.
|