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Applications of Ultrasound to Nasopharyngeal Carcinoma

Author: GaoYong
Tutor: ZhuShangYong
School: Guangxi Medical University
Course: Medical Imaging and Nuclear Medicine
Keywords: NPC Ultrasound MRI Nasal Endoscope
CLC: R739.63
Type: Master's thesis
Year: 2009
Downloads: 27
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Abstract


Objective To investigate the feasibility of ultrasound (US) applying to evaluate its value in the diagnosis of nasopharyngeal carcinoma(NPC).Methods Seventy-one patients suspected of having NPC were examined with US, nasal endoscope and magnetic resonance imaging (MRI). At US and Color Doppler Flow Imaging (CDFI), the following tumors characteristics were evaluated when tumors were found: location, size, margin definition, shape, echogenicity, vascularity and relationship of the parapharyngeal space. Membrana mucosas of left and right nasopharyngeal were contrasted when tumors were not found. By high frequency probe the enlarged lymph nodes of the neck were evaluated for size, shape, echogenicity and vascularity. Final diagnosis was confirmed by biopsy. For comparison of data obtained separately from US imaging, MRI and nasal endoscope,sensitivity estimates-that is, tumors or incrassate membrana mucosas-were calculated separately and analyzed by SPSS 13.0 statistical package.Results Seventy-one patients, the US findings for tumors were observed in 64.8% (46 of 71 patients), for incrassate membrana mucosas were observed 17 instances; for changes in parapharyngeal space were observed 25 instances; for enlarged lymph nodes were observed 57 instances; the MRI findings for tumors were observed in 46.5% (33 of 71), for incrassate membrana mucosas were observed 35 instances; for changes in parapharyngeal space were observed 44 instances; for enlarged lymph nodes were observed 56 instances; the nasal endoscope findings for tumors were observed in 78.9% (56 of 71), for incrassate membrana mucosas were observed 13 instances. Sensitivity estimates for the diagnosis of NPC were 88.7% for US, 95.8% for MR imaging, 97.2% for nasal endoscope. Sensitivity estimates for the diagnosis of NPC were not significantly different that between US and MRI (McNemar test, P=0.18) and that among US, MRI and nasal endoscope(Rank test, P=0.08).Conclusions Considerable picture quality of US and significant agreement among three groups indicate that it is feasible for US applying to NPC. US can provide a quite exactly judgement to NPC, cervical lymph node metastasis, the relationship between focus of infection and parapharyngeal space. US can provide an overall convenient and scientific evidence for clinical diagnosis and treatment.

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CLC: > Medicine, health > Oncology > Department of Otolaryngology tumor > Pharyngeal tumors
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