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Clinical Investigation on 308 Cases of Preterm Premature Rupture of Membrane

Author: GongZhiYong
Tutor: WuMingYuan
School: Zhejiang University
Course: Obstetrics and Gynecology
Keywords: PPROM Newborn Infection
CLC: R714.433
Type: Master's thesis
Year: 2009
Downloads: 89
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Abstract


Objective: To investigate the clinical incentives preterm premature rupture of membranes and different gestational age preterm premature rupture of membranes and premature rupture of membranes duration of maternal and child. Methods: Retrospective analysis of 2007 our hospital 308 cases of PPROM cases. An analysis of premature rupture of membranes incentives. Depending on gestational age were divided into 28-33 pregnant weeks (A) and pregnant 34-36 6 weeks (B) the two groups, respectively, from newborns asphyxia, infection, intracranial hemorrhage, respiratory distress syndrome, the differences automatically discharged and the incidence of death, as well as maternal dystocia rate and puerperal morbidity between the two groups; according to premature rupture of membranes time the cases were divided into < 18h ,18-72h,> 72h three groups, respectively, from the neonatal infection, intracranial hemorrhage, respiratory distress syndrome, and automatically discharged and the incidence of death, and dystocia rate and puerperal morbidity premature rupture of membranes time impact on maternal and child. Results: 1.52.3% PPROM prone factors exists, multiple pregnancy (45.45%), vaginitis (15.58%), twins or multiple births (14.61%) the breech (12.99%) as the main reason. With greater gestational age group (pregnant 34-36 6 weeks) compared to preterm membranes, smaller gestational age group (28-33 6 week) premature rupture of neonatal asphyxia, respiratory distress syndrome, infection, and intracranial hemorrhage incidence was significantly higher (P <0.01), neonatal discharges and mortality was significantly increased (P <0.01), mother dystocia rate and puerperal infection rate increased (P <0.05). For gestational age less than 34 weeks cases, miscarriage The longer the neonatal respiratory distress syndrome, the incidence of the less, but there was no significant difference (P> 0.05); neonatal infection increased incidence, the incidence of intracranial hemorrhage reduce, have a significant difference (P <0.05); neonatal discharges and reduction in mortality, but the difference did not reach significance level (P> 0.05). For gestational age at least 34 weeks of the newborn, premature rupture of membranes is the longer, the greater the risk of neonatal infection (P <0.01); premature rupture of membranes duration of occurrence of a negative correlation between the rate of respiratory distress, but not is no obvious correlation between the incidence of premature rupture of membranes duration significant difference; neonatal intracranial hemorrhage and neonatal discharges and deaths. Different mode of delivery of premature rupture of membranes time group analysis <18h, 18-72h, 72h three groups dystocia rate of 65.00%, 62.70%, 65.52%, and there was no significant difference (P> 0.05); The three groups of maternal puerperal morbidity were 6.67%, 10.32%, 19.35%, premature rupture of membranes longer the time, the higher the maternal puerperalism rate, there is a significant difference (P <0.05). Conclusion: PPROM is often associated with a variety of incentives, common multiple pregnancy, vaginitis, twins or multiple births and breech. PPROM cases smaller, gestational age, the higher the dystocia rate, neonatal hospital discharge and mortality, complication rates also increased. Gestational age less than 34 weeks, miscarriage increased neonatal infection rates, but to reduce the incidence of intracranial hemorrhage, and respiratory distress syndrome, the incidence of downward trend. Fetal gestational age of 34 weeks or more, due to the maternal and neonatal outcomes significantly improve, and premature rupture of membranes time the longer, the higher the maternal puerperalism rate, it is not necessary to miscarriage. Premature rupture of membranes duration does not affect the choice of the PPROM childbirth way.

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CLC: > Medicine, health > Obstetrics and Gynaecology > Obstetrics > Pathological delivery (abnormal delivery) > Fetus and appendages disorders > Premature rupture of membranes
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