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Objective To investigate the impact of different analgesia on postoperative stress levels and perioperative cardiovascular events . Methods 164 patients undergoing elective abdominal and lower limb surgery in 2007 ACC / AHA noncardiac surgery confining of perioperative cardiovascular system assessment and treatment guidelines in the low- risk group were randomly divided into five groups : clonidine group (D group , n = 42 ) , epidural group (E group , n = 30 ) , morphine group (M group , n = 30) , fentanyl group (F , n = 30 ) , remifentanil group (R group , n = 32). 5 groups inhalation combined with general anesthesia , Group E before induction of epidural cannulation tentative amount is given only to confirm catheter in the epidural space . Surgery then a dynamic ECG continuously recorded postoperative 48h to observe adverse cardiovascular events , and analgesic drug , except D group back to the original department ( as the control group ) , and the rest of the group fed SICU and Control Price -Henty score 1 to 2 minutes , respectively, before induction (T0), postoperative 2h (T2), after 24h (T24 ) , postoperative 48h (T48) acquisition venous blood samples were measured by radioimmunoassay , adrenocorticotropic hormone (ACTH ) , cortisol (Cort ) ; same time , intraoperative and postoperative information . 5 patients in the preoperative , intraoperative and postoperative data not statistically significant. No significant difference in 5 groups analgesic Price-Henry score at each time point . 5 preoperative cortisol , ACTH levels no difference in postoperative stress were elevated E group in T24 and T48 when the stress level is lower than the other four groups ( P < 0.05) . Postoperative incidence of cardiovascular events was not statistically significant ( P > 0.05 ) . Conclusion Epidural analgesia can reduce the postoperative stress levels , but no statistically significant difference in incidence compared with intravenous opioid analgesia , cardiovascular events .
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