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Objective: unstable angina patients with clinical manifestations and causes the machine that qi stagnation and phlegm group the Tongxinluo damage is important in the pathogenesis of phlegm meridians of qi and blood circulation is important governance law , and proposed parties active enjoyable drink , designed to observe the the Tongluo treatment of qi and blood and phlegm unstable angina clinical efficacy and to explore its mechanism . For the treatment group : clinical observation active the Western conventional treatment Jiashu heart drink routine western medicine for the control group , were observed in 60 patients (treatment group of 30 patients , 30 patients ) . Observe the clinical symptoms , ECG , blood pressure , blood lipids , blood rheology , CD62p , CD63 and other indicators . Animal experiments using 60 Wistar rats , copy isoproterenol-induced acute myocardial ischemia model , observed enjoyable active drink their ECG , SOD , MDA , the ET , TXB2 impact . Results: The clinical observation showed that the treatment group in improving clinical symptoms, and lipids , lower blood pressure , reduce blood viscosity and platelet activation than the control group ( P lt ; 0.01 or P lt ; 0.05) . Animal studies have shown that the comfortable active drink can significantly improve the rats with acute myocardial ischemia ECG ischemic changes , decrease MDA , ET , TXB2 increased NO levels and SOD . Conclusion: qi and blood circulation and resolving Tongluo relieve coronary spasm , improve endothelial function , scavenging oxygen free radicals , inhibition of lipid peroxidation , reduce blood viscosity and platelet activation , which play a retard atherosclerosis to prevent thrombosis the role of qi and blood circulation and resolving Tongluo the treatment of unstable angina conquer .
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