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Chinese medicine diagnosis and treatment of adjuvant therapy clinical study of AS

Author: LinWeiGen
Tutor: FangJian
School: Guangzhou University of Traditional Chinese Medicine
Course: TCM orthopedics and traumatology
Keywords: Prospective study Traditional Chinese medicine Ankylosing spondylitis Rattan drugs
CLC: R259
Type: Master's thesis
Year: 2009
Downloads: 60
Quote: 0
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Abstract


Aim of the present study is based on clinical findings mandatory spondylitis (AS) patients with mostly young patients, combined with the author tutor years of research experience of the disease, ankylosing spondylitis pathogenesis think the key is \Yang, damp Blockage veins \Chinese herbs treatment of the disease, and achieved satisfactory results. This randomized controlled study in parallel, through the adjuvant treatment of Chinese medicine diagnosis and treatment efficacy of AS, to explore Chinese medicine syndrome differentiation treatment of AS pathogenesis, therapy, prescription drug law for the development of Chinese medicine syndrome differentiation treatment mandatory spondylitis program provides a theoretical basis and clinical evidence. Methods In this study, the clinical diagnosis of ankylosing spondylitis patients for the study, a prospective randomized controlled trial, according to experimental groups: control = 1:1 total of 62 patients were randomly drawn by checking the random number table, after screening , in accordance with the patient treatment time for simple randomization, were given oral decoction of Chinese medicine syndrome differentiation Ghani nimesulide capsules, basic treatment with nimesulide capsules, basic treatment. Trial in strict accordance with the requirements of the last 62 cases were collected. Experimental group and control group patients had no depigmentation. Results two groups of patients before general information including age, gender, disease duration, the main symptoms, secondary symptoms, overall function grading, the difference was statistically significant (p> 0.05), consistent baseline before treatment. Conducted on two groups of patients were compared before and after treatment score, the test group of patients treated in clinical symptoms, overall function, laboratory parameters and other aspects to improve the situation significantly improved compared with before treatment, the difference was statistically significant (p <0.05): control group of patients treated in clinical symptoms, overall function, laboratory parameters to improve the situation, etc. are also a significant improvement compared with before treatment, the difference was statistically significant (p <0.05); experimental group and control group before and after treatment sacroiliitis x ray film classification did not change, the difference was not statistically significant (P> 0.05), but the experimental group after treatment sacroiliitis x-ray film classification performance compared with the control group, the difference was significant (P <0.05), described in the maintenance sacroiliitis stability condition of the test group than the control group a significant effect; while in the occipital wall distance change between the two groups no significant improvement compared with before treatment (p> 0.05). Two groups of patients rated the degree of improvement after treatment compared with which the clinical symptoms, the overall function, laboratory parameters to improve the situation, the experimental group than the control group, the difference was statistically significant (p <0.05), while the pillow wall distance, chest expansion and other aspects of the degree of improvement in both groups had no significant difference (p> 0.05). Conclusion Chinese medicine syndrome differentiation adjuvant treatment of ankylosing spondylitis, can significantly improve the patient's mental, behavioral conditions, activities of daily living and athletic ability. For the diagnosis of ankylosing spondylitis in patients with early diagnosis and treatment in Chinese medicine intervention in improving symptoms of AS patients, delaying disease progression and improve quality of life of patients achieved some clinical efficacy, worthy of promotion and further study.

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