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Objective: To compare Clinical efficacy of Traditional Chinese medicine Stroke （Acute Cerebral Infarction） Qi deficiency and blood stasis patients which treated by Tanshinone Injection and Tetramethylpyrazine Injection, want to know Whether Chinese medicine drugs injections need Clinical Drug Treatment election from Differentiations.Methods:1. Clinical Data80 cases of Acute Cerebral Infarction from of Affiliated Hospital of Hubei College of Traditional Chinese Medicine outpatient and hospitalized patients, divided into tanshinone IIA sodium injection group （hereinafter referred to Tanshinone group） and hydrochloric acid ligustrazine injection group （hereinafter referred to ligustrazine group） in randomized, parallel-controlled methods, by 1: 1 ratio, according to randomized , 40 cases each, followed by serial number delivery. Tanshinone group: sodium tanshinone II—A Injection 60mg, 5% glucose solution or 0.9% NaCl intravenous infusion of 250ml, 1st day, to share within 14 days; ligustrazine group: ligustra zine hydrochloride 80mg, 5% glucose solution or 0.9% NaCl intravenous infusion of 250ml, 1st day, sharing 14 days. Two groups of symptomatic patients received conventional treatment, including the regulation of blood pressure, blood sugar, anti-infection and intracranial pressure lowering treatment, if necessary. May not be observed during treatment with the test drugs increase the effectiveness of using the same or similar drugs with non-drug therapy.2. Clinical Observation of the efficacy:Stroke patients to determine the efficacy; Stroke patients to determine the efficacy of traditional Chinese medicine symptom; Clinical neurological deficits comparative the efficacy.3. Clinical Observation of the time :Clinical Observation on the 1st day and the 14th days. Laboratory tests of the efficacy of the investigation before and after treatment.4. The safety of the general situation observed: Temperature, heart rate, respiration, blood pressure, etc.;laboratory tests: blood, urine, feces （occult blood） test, electrocardiogram, liver function （ALT, AST, BUN, Cr, cranial CT or cranial MRI ）, in the pre-treatment and treatment of 14 days after the inspection and record the time, at any time to monitor adverse reactions.Results:1. Stroke patients to determine the efficacy analysisTanshinone group after treatment, the number of clinicalrecovery in 4 cases, 22 cases markedly effective, effective number of 10 cases,total effective rate was 90.0%; Ligustrazine group after treatment, the number of clinical recovery in 3 cases, 6 cases markedly effective, effective number of 11 cases, there is always efficiency of 72.5%. By Ridit test, two groups of effects were significantly different （P <0. 05）. Description Tanshinone on qi deficiency and blood stasis stroke patients to improve symptoms significantly better than the role of ligustrazine.2. Stroke patients to determine the efficacy of traditional Chinese medicine symptom analysisAfter treatment, in Tanshinone group, the number of clinical cure for the 3 cases, 22 cases markedly effective, 1 cases effective, the total effective rate was 90.0%; in Ligustrazine group, the number of clinical cure for the 2 cases, 16 cases markedly effective, valid 1 cases effective, the total effective rate was 77.5%. by Ridit test, two groups of effects were significantly different （P<0.05）. Tanshinone on stroke patients that qi deficiency and blood stasis syndrome in traditional Chinese medicine is better than the improvement Ligustrazine role.3. Clinical neurological deficits comparative analysis of efficacyAfter treatment, in Tanshinone group, the number of clinical curefor the 4 cases were cured , 19 cases markedly progress, 13 cases progress, total effective rate was 90. 0%; in Ligustrazine group, the number of clinical cure for the 3 cases were cured, 17 cases markedly progress, 17 cases progress, there is always efficiency of 80. 0%. by Ridit test, two groups of effects were significantly different （P<0. 05）. Description Tanshinone on qi deficiency and blood stasis disease stroke clinical improvement of neurological deficit is significantly better than the role of ligustrazine.4. Comparative analysis of securityTanshinone group and ligustrazine group in clinical observation, general conditions both are stable, two groups blood-Rt、liver and kidney function、conventional manure, fecal occult blood、prothrombin time、ECG、head CT or MRI abnormalities did not occur and no adverse response and toxicity. Conclusion:Through this clinical study confirmed the Traditional Chinese Medicine Tanshinone injection and ligustrazine injection in treating Traditional Chinese medicine Stroke Qi deficiency and blood stasis （acute cerebral apoplexy certainly ） effective, the Tanshinone injection is better than ligustrazine. Demonstrated in clinical medicine for intravenous drug preparation for Traditional Chinese Medicine syndrome differentiation is necessary to prove that the Traditional Chinese Medicine Syndrome Differentiation of intravenous drug selection can improve the clinical efficacy of drugs.
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