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Purpose of hemorrhagic stroke is a common disease in the elderly, has a high incidence and high mortality, high morbidity, complications, and over the years has been one of the major cause of death in the human. Explore to minimize effective treatment for the disease, mortality, morbidity, is one of the important subject of the present study. The application of the subject of rhubarb with the conventional treatment of acute cerebral hemorrhage, to Tongfu Xiere, cooling blood to stop bleeding, the blood stasis conquer Clinical observation and control XNJI to explore the mechanism of its efficacy, for further provide a good basis to carry out the in-depth study of the treatment of acute cerebral hemorrhage rhubarb. Method 1. Clinical data in all cases from April 2005 to August 2008 Hubei Provincial Department of Neurology, Hospital of hospitalized patients with a total of 56 cases. Randomly divided into the raw rhubarb treatment group and Xingnaojing Injection control group, treatment group of 28 cases and 28 cases of the control group. Two groups in age, sex, duration of treatment before stroke disease integrator, the degree of neurological deficit Points, TCM syndrome score, the size of the intracranial hematoma fundamental equilibrium, statistical analysis, no significant difference (P> 0.05), has comparable. 2. Treatment group medication: 6 ~ 10g rhubarb decoction fifteen minutes, the juice 150ml 2 to 3 times a day orally. Not eating or drinking fat choking, can be applied to the nasal feeding, the amount of the same oral dose. Control group medication: XNJI, 10ml / support, 20ml / adding intravenous infusion of 5% glucose or 0.9% sodium chloride solution 250ml, 1 times / day. The treatment lasted 14 days. Two groups during treatment were given basic treatment, if necessary, give suctioning, oxygen, and reduce intracranial pressure support therapy; disable other treatment of acute cerebral hemorrhage drugs and drugs that may affect the observed results. Security check of the efficacy and safety were observed in 7 and 14 days of treatment the day before the test, each observation and recording time; Efficacy of indicators before and after each treatment once. 4. Statistical Methods SPSS13.0 software data for statistical analysis, count data with X ~ 2 test, measurement data using t test, ranked data Ridit test. Results 1. Clinical neurological deficit degree of efficacy control group comparison: After treatment, the basic one cases were cured, 9 cases of significant progress, progress in 14 cases, no change in the four cases, the deterioration of the O cases, the total effective rate was 85.7%; basic recovery 0 cases, significant progress in eight cases, progress in 15 cases, unchanged in five cases, the deterioration of 0 cases, the total effective rate of 82.1%. Statistical analysis, the total effective rate comparison was no significant difference (P> 0.05). 2. The TCM syndromes comparison: two sets of TCM climate in varying degrees of improvement, the treatment group after treatment was 0 cases, 10 cases markedly effective in 13 cases, 5 cases ineffective, the total effective rate was 82.1%; controls The basic group 0 cases were cured, 8 cases were markedly effective in 14 cases, 6 cases, with a total effective rate of 78.5%. After statistical analysis, the treatment group and the control group, the total efficiency is no significant difference (P> 0.05). Degree of neurological deficit score between the two groups before and after treatment, the two groups of patients before and after treatment itself four scoring stroke of TCM syndrome and signs score, the stroke disease clinical performance score, the total life capacity state ratings comparison: comparison, The test itself compared differences in scores was statistically significant (P <0.01); rated in the treatment group and the control group after treatment showed no significant difference (P> 0.05), rhubarb apoplexy improvement noticeable effect. The treatment group and the control of the two groups before and after treatment head CT examination showed changes in the amount of bleeding: After treatment, intracranial hematoma absorption than before treatment, Self comparative difference was statistically significant (P <0.01); Group intracranial hematoma absorption contrast is not obvious, the two groups showed no significant difference (P> 0.05). Rhubarb can help speed up the absorption of intracranial hematoma. Adverse reactions and side effects: the treatment group and the control group during the clinical drug does not appear significant adverse reactions and side effects. The laboratory test results (three conventional ECG, liver and kidney function, blood clotting function) before and after treatment were not drug-related abnormal changes. Description rhubarb no significant adverse reactions and side effects. Conclusion The study results show that: the treatment group students the rhubarb and the control group XNJI the clinical neurological deficit scale efficacy rated stroke disease TCM syndrome and signs score, the apoplexy clinical performance score, total life status score, TCM The syndromes comparison intracranial hematoma absorption compared by statistical analysis, no significant difference (P> 0.05). Show that rhubarb combined with conventional treatment a significant role in promoting the improvement of neurological deficit of stroke (brain hemorrhage), like the improvement of TCM have a significant effect, but also make intracranial hematoma absorption. Description rhubarb is an effective drug for the treatment of acute cerebral hemorrhage.
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