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Noninvasive Ultrasound Estimation and Visualization of Tissue’s Temperature Field

Author: LiWei
Tutor: XiaoXiangZuo；NiuJinHai
School: Shanghai Jiaotong University
Course: Biomedical Engineering
Keywords: Ultrasonic nondestructive testing Ultrasound Hyperthermia High Intensity Focused Ultrasound Temperature field
CLC: TH878
Type: Master's thesis
Year: 2009
Downloads: 88
Quote: 0
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Abstract


High-intensity focused ultrasound therapy (HIFU) is one of the important means of cancer treatment, it will sound intensity ultrasound energy focused on the tumor internal, local produce instant high temperature reached solidification temperature caused the death of the cancer protein, in order to achieve therapeutic purposes. To kill the cancer cells without damage to normal tissue temperature monitoring will directly affect the therapeutic effect of tissue injury evaluation and tissue temperature monitoring is very important, it is during the HIFU treatment. The traditional lossy temperature measurement method will give the patient painful and prone to metastasis, its application has been very limited. Ultrasonic nondestructive temperature measurement method because of its relatively low cost, and easy to be compatible with the treatment system has drawn greater attention. By utilizing HIFU and monitor digital B super set suitable for HIFU treatment temperature measurement system, and the reference to the actual use of the system and treatment conditions vitro experiments by different methods HIFU irradiation organization B- image analysis, to explore the parameters of tissue temperature with B-mode images, its main work: (1) on the basis of the analysis of the ultrasonic measurement principle the noninvasive temperature experimental system design uniform slow heating, ultrasound images of biological tissues, and its Correlation of the temperature. The system consists of the B-device, thermostat heating tanks, the digital thermocouple collection instrument, image acquisition card and computer. (2) designing and writing software systems, software features include: of HIFU source emission control, experimental image acquisition and storage, digital thermocouple temperature acquisition and storage, image processing, data processing and analysis, and visualization of the results for noninvasive temperature display, and threshold setting and alarm. Non-destructive testing and display of real-time temperature in the tumor hyperthermia. (3) fresh vitro pork and chicken heart as the research object to study the changes in the parameters of the characteristics of B-water bath heated biological tissue. By a large number of experimental data analysis of the relationship between the grayscale characteristics of the B-mode images of the tissue temperature. Studies have found that: when the temperature of the biological tissue in less than 60 ℃, parts of the gray-scale variation of the biological tissue of interest, and temperature changes are substantially linear relationship, to achieve the possibility of temperature measurement and control lossless. (4) the fresh pork vitro research object, a change in the region of the HIFU heating biological tissue temperature rise. Wiener filter, gray threshold, corrosion expansion, enhanced by the pseudo-color image processing means to achieve a visual expression of tissue temperature. To some extent reflects the tissue ablation, pursuant to the monitoring of thermal coagulation zone change and assess efficacy.

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CLC: > Industrial Technology > Machinery and Instrument Industry > Instruments, meters > Material testing machine and test equipment > Nondestructive flaw detector
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