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Retrospective Analysis and Pathological Study on Patients with Oral Submucous Fibrosis Coexisted with Oral Lichen Planus

Author: MengQingYu
Tutor: PengJieYing
School: Central South University
Course: Clinical Stomatology
Keywords: The oral mucosa fiber become Oral lichen planus Clinical manifestations Pathology
CLC: R781.5
Type: Master's thesis
Year: 2011
Downloads: 5
Quote: 1
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Abstract


The purpose of this project by collecting 57 cases by clinical and pathological diagnosis of OSF coexist OLP cases, complete records of patients with clinical data and pathological diagnostic data for statistical analysis, to explore the relationship between the clinical features and pathological changes OSF coexist OLP patients , to lay the foundation for further research. Design tables, sorting patient's sex, age, and chewing betel, clinical symptoms and signs and pathological diagnostic data and other information in accordance with the original data of the patients. Collect the above information is complete the pathological diagnostic data of 57 cases of samples, including pathological diagnosis report, biopsy and pathological wax block. In light microscope biopsy, detailed records of pathological changes, clear OSF staging and OLP pathological changes characteristic. The results of 57 cases of OSF with OLP patients, 55 males and 2 females, the male to female ratio was 96.5%, 3.5%. The most common patients 20-29 years, 30-39, two age groups, 20-29-year-old, 30-39-year-old, 40-49-year-old, 50-59-year-old four ages of the patients, respectively, 21, 23 , 7, 6. Chewing betel 1 year, 1-3 years, more than three years, respectively, for the 20 cases, 27 cases, 10 cases. 57 patients have obvious OSF change common site followed by wing mandibular ligament area, soft palate, tongue, cheek, all 57 cases, 18 cases, 15 cases, seven cases. 57 cases of OSF partners OLP patients, the OLP lesion were cheek (35 cases), tongue (19 cases), gums (3 cases), the proportion of various parts were 61.4%, 33.3% and 5.3%, respectively. Lesion types to white striped changed the most common, accounting for 66.7% of all lesion types, followed by white plaque-like changes in the accounting for 21.1%, the tongue tongue papillary atrophy in seven cases. All cases showed no erosion. OSF associated with 57 cases of OLP patients, epithelial hyperplasia cases, 40 cases, 17 cases of epithelial atrophy cases (Figure 3-6), the proportion was 70.2%, 29.8%, respectively. OSF associated with 57 cases of OLP patients, connective tissue are visible characteristic changes of the collagen fibers OSF. Which filamentous collagen fiber cases in 22 cases, the accumulation of collagen fibers, 28 cases, not completely hyalinized collagen fibers completely hyalinization cases of seven cases, the proportion of 38.6%, 49.1%, 12.3% . The OLP patients Conclusion 1.OSF coexistence of the majority of men 20-39 years of age. The male to female ratio is 27.5:1.2. OSF coexist OLP patients simultaneously with clinical signs and symptoms of OSF, OLP, but not due to simple OLP result in erosive damage and pure OSF tongue movement and limited mouth opening signs. 3.OSF coexist OLP patients with lesions in the OSF early, mid-, oral mucosal epithelial hyperplasia.

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CLC: > Medicine, health > Oral Sciences > Oral medicine > Oral mucosal disease
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