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Objective: With the improvement of scientific and technological progress and economic level, the implant denture has gradually become the preferred means of Prosthodontics. How to better improve the binding rate of the implant and bone tissue, accelerate the healing of bone tissue after a hot research scholars and newborn. At present, research on this problem mainly in the bone growth factor, but the clinical application of exogenous growth factors exist sources of exogenous factors, costs, immune response and side effects, due to the defects of the carrier gene The treatment is also limited to research in this area has no major breakthrough. To find an effective, economical, convenient application methods to promote new bone growth around the implant, and to promote earlier and better with the implant to ensure that the dental implant success has Pozaimeishao the. The experimental observation rabbit planting after the operation the new injury Dipsacus soup treatment, the combination of the implant and the bone tissue and bone around the repair freshmen, is designed to explore the role and contribution of the theory of traditional Chinese medicine to modern medical treatment, seeking economic convenient and practical method for clinical application. Methods: 32 Japanese white rabbits (weight 2.5 to 3kg), nano-hydroxyapatite the particle sintering implant 256. 4 each side of each rabbit iliac bone implant. After 32 rabbits were randomly divided into two groups, the experimental group was given Chinese medicine decoction, twice daily, each 15ml, 2 weeks, the control group was given the same amount of saline. Preoperative and postoperative every two weeks in the marginal ear vein blood samples were approximately 0.5ml serum alkaline phosphatase and serum calcium, phosphorus. Rabbit (except rabbits were sacrificed 2 weeks) were killed two weeks before, one week subcutaneous injection of tetracycline hydrochloride. Were two weeks, four weeks, eight weeks, the control group, the experimental group were sacrificed 2 rabbits, remaining rabbits were sacrificed at 12 weeks. Interception of bone tissue with implants were killed after 256. Four of the specimens OUTCOME MEASURES: specimens, x-ray observation, the making hard tissue slices fluorescent microscopy, scanning electron microscopy. The data will be analyzed by statistical software spss 16.0, t test. Results: 1. Serum alkaline phosphatase peak serum alkaline phosphatase and serum calcium, phosphorus results: experimental group than the control group as early as its peak value higher than that in the control group, after 10 weeks, basically reduced to normal range, while the control group until 12 weeks to return to normal levels. 2 weeks after surgery, the animals of the experimental group and the control group calcium have different levels of elevated serum phosphorus decreased thereafter, two sets of blood calcium showed decreased. 2 specimens observation: all animals surgical wound healed well, the naked eye can see no implant loosening, shedding, and linked closely together between the iliac, multi-bone integration. Two weeks specimens of some area visible thin layer of fibrous tissue. The 3.X lines observed: 4 weeks specimens, the density is higher than that in the control group, the experimental group and the experimental group looming bone trabeculae. 8 weeks specimens, the experimental group around the implant transmissive region disappeared, implant and surrounding bone are linked closely together, the control group, there is still small the transmissive region density compared with experimental group. 4 fluorescence microscope: 4 weeks specimens, thick, dense trabecular bone of the experimental group than in the control group. 8 weeks specimens, the experimental group around the implant visible long cord-like continuous band of light, there have been continuous new bone trabecular calcified bone, the control group in the peri-implant light with shorter, discontinuous, and compared with experimental group. 12 weeks specimens, the experimental and control groups around the implant are visible ring fluorescence with two consecutive, two light with intervals experimental group is slightly wider than in the control group. Scanning electron microscopy: two weeks, four weeks, eight weeks specimens of the experimental and control groups in both bone and implant gap. Two weeks, four weeks due to a larger gap, embedding polymethyl methacrylate infiltration between the bone and the implant. 12 weeks specimens, the experimental group, the bone implant closely integrated, but there is still a small gap in the control group, and 2000 magnification around the implant visible the clear continuous gap located between the bone and the implant. Conclusion: taking new injury Dipsacus soup can promote the proliferation of osteoblasts, its amount and activity were increased to speed up the process of bone regeneration, bone repair and healing completed ahead of schedule, thereby enhancing bone implant after implantation combination.
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