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Objective: Observe the Jianpisanjiehuathuoxue method oral administration. methods joint rhubarb jiedu decoction for drug treatment of liver cirrhosis colon clinical effect. Methods: 60 patients with cirrhosis were randomly divided into treatment group (30 cases) and control group (30cases),the two groups were both treated with Chinese medicine of the method of jianpisanjiehuatanhuoxue, give ShuiGong hanako decoction orally. The treatment group were treated with retention-enema of Rhubarb Jiedu Decoction additionally, once-daily for 12 weeks. Observe two groups before and after the treatment main symptoms, signs, relevant inspection index. Results: Both groups can improve liver function, blood coagulation, blood endotoxin, inflammation index, liver ultrasound measurement indexes and the liver fibrosis degree. The treatment group in improve liver function, reduce blood endotoxin, improve liver fibrosis degree, improve pee color yellow, loose stools, abdominal distension, etc curative effect than control group(P<0.05).The total effective rate of the treatment group( 76.67%) is superior to that of control group (56.67%) (P<0.05). Conclusion: The curative effect of the method of jianpisanjiehuatan with Chinese medicine on cirrhosis is remarkable. Colonic drug could be an effective treatment for the patients with cirrhosis enterogenous endotoxin hematic disease,and add a rhubarb jiedu decoction can improve treatment for medicine colon clinical curative effect of cirrhosis
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