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Study of Synthesis of P-acetylaminophenol and Analogues of P-acetylaminophenol Through the New Technology

Author: LiJingFeng
Tutor: ZhangYouMing；WeiTaiBao
School: Northwest Normal University
Course: Inorganic Chemistry
Keywords: Synthesis Catalyst Aminophenol Acetylamino phenol Paracetamol analogues One-pot New technology
CLC: TQ463.2
Type: Master's thesis
Year: 2009
Downloads: 273
Quote: 0
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Abstract


This paper includes the following chapters: Chapter 1 : Progress in the synthesis of acetaminophen This chapter reviews the recent years by the different starting materials synthesis method of acetaminophen , through the comparison of different starting materials and their methods , from the environmental on up to consider the economic , phenol as raw material one-pot synthesis method will be the preferred method of synthesis of acetaminophen . Chapter II: a new process of a synthetic acetylamino phenol chapter zinc powder as the catalyst and an antioxidant , to p-aminophenol and acetic acid as raw materials , high purity, high yield synthesis of the APAP . Product by melting point and NMR card table . Finally review the advantages of the process . Chapter : One-Pot Synthesis of new technology acetaminophen This chapter examines the case as a catalyst in the PPA , the raw pot synthesis of phenol , glacial acetic acid , hydroxylamine hydrochloride acetaminophen new technology . Product by melting point and NMR card table . Last reviewed pot synthesis acetylamino phenol process advantages . Chapter IV: One-pot Synthesis acetaminophen analogs new process chapter in PPA as a catalyst in the case , the new process to the phenol, propionic acid or butyric acid, hydroxylamine hydrochloride as the raw material pot synthesis of acetaminophen analogs . The prima facie evidence of the product by melting point and infrared spectrum .

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CLC: > Industrial Technology > Chemical Industry > Pharmaceutical chemical industry > Production of organic compounds in drug > Aliphatic compounds, drugs
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