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Survey ECM Carrier Rate and the Level of Serum Antibody in Healthy Population in 2005/2006 and 2006/2007 in Hefei

Author: JinYuHui
Tutor: SuHong
School: Anhui Medical University,
Course: Public Health and Preventive Medicine
Keywords: Healthy people ECM Carrier rate Serum antibody levels
CLC: R515
Type: Master's thesis
Year: 2008
Downloads: 20
Quote: 0
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Abstract


Objective To understand the of Hefei health crowd in 2005/ 2006 , 2006/ 2007 period the ECM carrier rate and changes in antibody levels for ECM prevention provide the basis . Counties cluster sampling , stratified sampling by age in the county district , kindergarten, elementary, junior high , high school students and adults were selected for sampling , continuous monitoring of the healthy population for two consecutive years at different times the ECM carrier rate and serum antibody levels . The results of monitoring of 5495 , the total carrier rate of 5.0% , the highest infection rate of group C , 2.5% ; two popular annual total carrier rate with ECM before , late in rising popular . The carrier rate of the 16-18 age group was the highest . A healthy population of the meningitis vaccine immunization history carrier rate was significantly lower than non- immunization history crowd . Serum antibody monitoring 4090 A group of antibody positive rate was 83.7 % , GMT 1:201.4, C group antibody positive rate was 72.2%, GMT as 1:178.1 ; 2006 / 2007 group C antibody levels lower than the 2005 / 2006 obvious. Group A and group C ECM antibody levels were rising with the time extension of epidemic cerebrospinal meningitis epidemic ; healthy population of the three counties of Group C antibody positive rate and GMT was higher than urban . A group of people of different ages antibody levels were higher than the C group , the kindergarten toddlers and adults group A antibody level lower than that of other age , the C cluster antibody levels increased with age gradually reduced . The vaccination AC meningitis vaccine antibody positive rate was 55%, GMT to 1:96.6 . Conclusion C serogroup has become a new advantage in Hefei popular flora , healthy population of antibody levels significantly lower than the A group , and did not achieve the desired level of protection . With popular time of the extension of a cerebrospinal meningitis epidemic season the ECM carrier rate of healthy people and serum antibody levels are constantly elevated . Healthy population group C antibody levels decreased significantly with increasing age , vaccination rates AC meningitis vaccine in the Expanded Programme on Immunization of older adolescents and adults should be prepared . Vaccination AC meningitis vaccine should be timely to strengthen the immune ensure the persistence of the immune .

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CLC: > Medicine, health > Internal Medicine > Infectious disease > Bacterial infection,bacterial infectious diseases
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