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Research on Application of the FNN Inverse Soft-sensing Method in the Penicillin Fermentation Process

Author: LiuZuo
Tutor: SunYuKun
School: Jiangsu University
Course: Detection Technology and Automation
Keywords: Penicillin fermentation Soft Measurement Inverse system Fuzzy Neural Network VC Matlab
CLC: TQ465.1
Type: Master's thesis
Year: 2010
Downloads: 56
Quote: 0
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Abstract


Penicillin was the first antibiotic used for purification of large-scale human clinical demand for the world 's largest antibiotics . Penicillin penicillin fungus secondary metabolites , fermentation of complex biochemical reaction mechanism , the performance of the dynamic behavior of complex and changeable, nonlinearity and uncertainty . Lack of a biosensor , some key biological parameters difficult to achieve online measurement, making it difficult to achieve the optimization of the fermentation process control . The soft measuring technique provides an effective way to solve such problems . In this paper, the penicillin fermentation process online soft measurement technology and engineering practical study key biomass . Penicillin fermentation process inverse system is established , the application of soft fuzzy neural inverse measurement method for online measurement and clarify the the soft measurement application software design and implementation methods . ( 1) based on the non - structural dynamics model of penicillin fermentation process , based on constructed penicillin fermentation process virtual subsystems \fuzzy neural inverse soft measurement model . (2) three separate fuzzy neural network to approximate nonlinear function of the inverse system , fuzzy clustering algorithm neural network is introduced to avoid excessive number of rules , the use of gradient descent learning algorithm to adjust the network parameters . The network structure is relatively simple , and can better reflect the characteristics of the input and output sample rate and generalization ability of the neural network training . (3 ) In accordance with the program modular thinking penicillin fermentation process fuzzy nerve inverse soft measurement system software . VC to create a user interface application call in MATLAB soft measurement algorithm , the background database selection ACCESS, the overall design and detailed design , and the specific features of the various sub-modules . The test showed that the higher accuracy of the forecast system key state variables of the fermentation process can basically achieve the design objectives and requirements , and provide a basis for advanced control of the fermentation process .

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CLC: > Industrial Technology > Chemical Industry > Pharmaceutical chemical industry > Antibiotics manufacture > Penicillin and its derivatives
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