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Antimicrobial peptides ( Antimicrobial Peptides ) is an important part of the innate immune times exist in bacteria, fungi, plants , insects , birds , amphibians , mammals and even humans Defense peptide active substances . They are generally from about 4-50 amino acid composition, constitutes like the alpha helix , beta folding and annular secondary structure . Antimicrobial peptides also found in recent years , in addition to having anti-bacterial and anti - fungal activity we are familiar , having the function of the anti-viral , anti-cancer activity , mitogenic effect , and acts as a signaling molecule . These different antimicrobial peptides consisting of efficient, broad-spectrum defense system , also known as \This research will amphiphilic peptides V13K is the parent polypeptide to study its anti-tumor activity and its influencing factors . Designed from scratch means , by amino acid substitution sites in different regions to change the hydrophobicity of the polypeptide molecules , amphiphilic . V13K analogs using solid phase peptide synthesis techniques , the use of circular dichroism , high performance liquid chromatography temperature curve technique to study the secondary structure of the peptides and molecular self - interaction ; through a variety of cancer cells in vitro activity of experimental and bare rat in vivo preliminary screening test polypeptide anticancer activity , and to compare the activity of the polypeptide of normal human cells such as red blood cells . Anti-cancer peptide with high selectivity for cancer cells to anti-cancer therapy and anti - cancer drug development to bring new hope , anti-cancer peptide may become an alternative to traditional chemotherapy drugs , new peptide anticancer drugs .
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