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Objective: The purpose of this study is to investigate the leveling Tablets hypertension with anxiety improve the situation and go on plasma norepinephrine (NE), epinephrine (E), 5 - hydroxytryptamine (5-HT) affect, Try to explore the buck and improve the state of anxiety because. Methods: Type I design research methods randomized controlled trials, attached to a hospital of Cardiology inpatient departments and outpatient charge from the Guangzhou University of Traditional Chinese Medicine to meet the requirements of the hypertension associated with 60 cases of patients with anxiety states, a simple randomly divided into two groups, treatment The group was given a leveling Tablets to redouble their Perindopril therapy, the control group were treated with perindopril. By observing the clinical symptoms before and after treatment, blood pressure, clinical symptoms in the score, and state anxiety score, quality of life score, plasma NE, E, 5-HT to improve the situation and security observation to explore the therapeutic effect of leveling Tablets and effect mechanism. Results: 1, the two groups of patients before treatment, age, gender, type of TCM, anxiety levels constitute the ratio of inspection no significant differences (P gt; 0.05), comparable. 2, hypertension associated with anxiety state 60 patients, the antihypertensive effect: the treatment group, 15 cases, 10 cases, 5 cases ineffective, the total efficiency of 83.3% in the control group, six cases markedly effective in 17 cases, 7 cases , the total effective rate was 76.7%; Chinese medicine efficacy: treatment group, 5 cases markedly effective in 16 cases, 9 cases, the total efficiency of 70% of the control group, three cases markedly effective in 9 cases, invalid 18 cases, with a total efficiency of 40%, improve dizziness: treatment group, 16 cases, 10 cases, 4 cases, the total effective rate of 86.7% in the control group, 7 cases were markedly effective in 18 cases, 5 cases ineffective, the total effective rate was 83.3%, improving insomnia symptoms: treatment group 7 cases were markedly effective in 18 cases, 5 cases ineffective, the total effective rate was 83.3%, the control group, six cases markedly effective in 18 cases, 6 cases, the total efficiency of 80%; Hamilton integral two groups of patients before and after treatment, quality of life scores compared significant difference between the two groups, there are statistically significant difference; comparison of two groups of 40 cases of patients before and after treatment, plasma NE and 5-HT, E concentration, a statistically significant difference between the two groups have a significant difference . 3, after the taking of our group of patients, does not appear adverse reactions and side effects, comparison of patients before and after liver and kidney function, and no significant difference between the two groups. Conclusion: 1, leveling Tablets the homemade Chinese patent medicine of Guangzhou University of Traditional Chinese Medicine, nourishing the liver and kidney, Yu Yin grabbing Yang, soothe the nerves promoting blood circulation, tone flat yin and yang effect, not only can collaborate buck more effectively relieve patient anxiety. Statistical analysis showed joint leveling Tablets to assist the buck, to relieve symptoms and to reduce the level of anxiety, and improve the quality of life is significantly better than the control group, and effectively improve the patient's plasma NE, E, 5-HT concentration to provide a theoretical basis for leveling Kang tablets in the treatment of hypertension with anxiety state. Leveling Tablets is a safe and effective and reliable drugs worth more large-scale clinical studies and more detailed pharmacological studies.
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