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Objective: Oxidative stress is a common organism animal production status, a serious impact on the body's health and animal production performance of the play. In this experiment, multiple antioxidants under oxidative stress conditions in the animal metabolism of free radicals on the body level regulation, research multiple antioxidants, oxidative stress and free radical metabolism investigate the relationship between free radicals on the body function under stress effects achieved through nutritional control technology to improve the body's ability to resist oxidative stress and animal performance of the play. Methods: Test one: selection of 35 healthy male KM mice as research subjects were randomly divided into seven experimental groups of five. Quiet control group and the control group was fed the basal diet swim the remaining 5 were fed the basal diet fortified with vitamin C, vitamin E, polyphenols, antioxidants and complex microbial antioxidant diets. Observed during the test mice in each group growth; After the experiment, except for quiet control group, all mice were exhaustive swimming test, recording swimming time; and calculate the mouse organ index, MDA in serum were measured , SOD content and liver tissue NOS, CAT content. Test 2: Select nine litter 23-day-old piglets were randomly divided into three groups of three litter control group was fed the basal diet, test a group of micro-organisms in the basic dietary-derived antioxidants, group 2 in the basic composite dietary antioxidants. 21 days trial period, piglets weaned at 30 days of age unity. Observed during the test group piglets and feed consumption, and calculate weight gain and feed conversion ratio. Respectively, in the test section 1,8,15 days, each three piglets anterior vena cava blood, analysis of serum MDA, SOD, NO and GSH-Px content. Results: Test one: Compared with the control group, quiet, exhaustive swimming makes mouse serum MDA increased 22.86%, serum SOD activity significantly increased 94.98%, liver CAT activity increased 12.74%, NOS activity was significantly increased 27.90%; compared with the control group, swimming, composite antioxidant content of MDA in serum of mice significantly decreased 37.66%, SOD activity was significantly increased 20.44%, liver CAT activity increased 46.43%, NOS activity increased by 28.86%, and the differences were significantly (P lt; 0.05). Multiple antioxidants can make the mice swimming time was significantly increased 199.26% (P lt; 0.05), multiple antioxidants on mouse body weight and thymus, spleen index has increased role, but the difference was not significant (P gt; 0.05). Test two: weaning 1d and 7d serum MDA levels were higher than before weaning 7d significantly increased 24.67% and 16.51% (P lt; 0.05); weaning 1d in serum SOD, GSH-Px activity were compared before weaning 7d improve 2.87% and 25.96%, NO levels were significantly increased 32.19%; while weaning 7d in serum SOD, GSH-Px activity and NO levels were higher than after weaning 1d decreased 6.05%, 15.86%, 11.75%, and respectively, compared with pre-weaning at 7d low 3.35%, 25.96% high, high 16.66%. Compared with the control group, in feed multiple antioxidants, make piglets after weaning 1d serum MDA decreased 6.77%, SOD, GSH-Px, NO were increased by 11.61%, 25.10%, 19.55%; 7d piglet serum after MDA levels decreased 7.32%, SOD, GSH-Px, NO were increased 11.76,25.10%, 19.55%, and the difference was significant (P lt; 0.05). Another compound antioxidants improve ADG and feed compensation trends. Conclusion: Oxidative stress can lead to animal body to produce a large number of free radicals, lipid peroxidation enhancement, body damage, resistance to fatigue and decreased antioxidant capacity. Multiple antioxidants can remove the body from a variety of free radicals and improve the body's resistance to fatigue, oxidation resistance of the material composition, but also between the various components to achieve better synergies, so it has a better than other single antioxidant scavenging free radicals. Exercise stress by giving mice and piglets composite antioxidant supplement, has increased significantly in mice swimming time, mice and pigs decreased lipid peroxidation, increased antioxidant enzyme in mice and pigs play antioxidant capacity effect. Experiments show that multiple antioxidants can improve the animal's resistance to oxidative stress, and promote animal performance of the play.
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