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Primary Sjogren's syndrome (Primary sicca syndrome, PSS) is considered to be an infringement of the exocrine glands (salivary glands, lacrimal gland) based chronic systemic autoimmune disease, one for clinical incurable diseases. Patients often obvious eye and mouth dry, recurrent parotid swelling and joint pain is characterized by clinical manifestation and severity of different, can affect multiple systems of the body, such as skeletal muscle, lungs, liver, kidneys, digestive tract, blood vessels, nerves, and other organizations, and seriously affect the life and health of the patient. In the treatment of Western medicine PSS treatment is mainly symptomatic treatment. When the patients symptoms, such as lung disease, vasculitis, pseudolymphoma, you can use glucocorticoids or immunosuppressants, but these drugs have side effects and efficacy for the treatment of this disease is not yet certainly, there is a dispute. In short, the lack of effective treatment for PSS lack of effective therapy, the disease needs to be further explored. Chinese medicine in improving symptoms, control disease condition, significantly alleviate the side effects of the hormone and immune inhibitor efficacy, can reduce the rate of recurrence of the disease, and to improve the quality of life of patients. The national name of the old medical scientist Professor Lu Zhi is the first to propose a \The research of Professor Lu Zhi is personally guided by scientific and reasonable method evaluation Road, Old Yiqiyangyin of Ganliang moisten method the clinical efficacy of the treatment of this disease the implementation of observational studies to reveal the theory of Traditional Chinese Medicine permanent cure disease inherent law. The program uses a prospective, randomized, the treatment of drug and placebo crossover controlled, single-blind clinical trial methods. Collected to comply with the standard of the dry Bi Qi Deficiency of 66 patients were included in this study. Randomly included cases were randomly divided into a treatment group and the control group 30 cases, the two groups are divided into two-stage treatment drugs (Road's AIDS dry drink) and control drugs (Analog agent), the course of treatment is six weeks each, two-phase interval with a 2-week washout period, the total course of treatment to 14 weeks. The total effect of the evaluation of patients with diseases, TCM syndrome, improvement of symptoms of dry mouth, dry mouth symptoms efficacy, non-irritating mixed salivary flow rate improved laboratory improve the situation, the conclusions are as follows: 1, the research proved that 14 weeks after treatment, the two groups were apparent efficacy, efficiency is not less than 90% of the treatment group and the control group, the treatment group and the control group. Clinical control of the number of patients treated group was 4, the control group, two groups of seven patients complete control. 2, after the end of the total course of treatment, the two groups of patients with syndromes integral and improved significantly. Treatment group was 86.67%, the control group, the total effective rate was 87.10%, the treatment group and the control group, the total effective rate of 86.89 percent, said Mingzi dry drink efficacy, Zi dry drink for PSS TCM symptom score well effect. Symptoms of dry mouth efficacy, treatment group total effective rate was 90.00%, the control group, the total effective rate was 90.32%, the treatment group and the control group, the total effective rate was 90.16%, the integral efficacy of the two groups of patients with dry mouth symptoms improved significantly. 4, after the end of treatment, the treatment group and the control group, two groups of non-irritating mixed salivary flow rate test results compared with results no significant difference, said Mingzi dry drink a considerable improvement of the two groups of patients with salivary flow rate. 0 weeks of the treatment group compared with 14 weeks of non-irritating the mixed saliva flow rate test results statistically significant curative effect, said Mingzi dry drink for the treatment of patients with salivary flow rate improved significantly. Control group 0 weeks compared with 14 weeks of non-irritating the mixed saliva flow rate test results, no significant difference in treatment was stopped. 5, the comparison between serum RF level group after treatment, significantly lower in the treatment group compared with the control group, the rest of the immune indicators group comparison, there was no significant difference. With before treatment, compared to baseline, 14 weeks serum RF levels were significantly lower in the treatment group after treatment, I indicators before and after treatment comparison, no significant differences. 6, the treatment group and the control group before and after blood, urine, stool routine and biochemical examination numerical comparison, there was no significant difference in the road's AIDS dry drink in the treatment of PSS safe and reliable, no adverse reactions. 7, the treatment group after treatment, 14 weeks serum ESR and CRP are significantly lower, p lt; 0.05, statistically significant, and I was no significant difference in the index before and after treatment. ESR of the control group were significantly lower, P lt; 0.05 no significant difference in CRP before and after treatment.
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