Dissertation > Excellent graduate degree dissertation topics show

A New Technic of Extraction and Separation of Panax Notoginseng Total Saponin

Author: LiChunLing
Tutor: WeiTengYou
School: Guangxi University
Course: Chemical processes
Keywords: Panax Notoginseng total saponin extraction separation
CLC: R284.2
Type: Master's thesis
Year: 2008
Downloads: 1042
Quote: 6
Read: Download Dissertation

Abstract


Panax Notoginseng（PN） is one of the precious traditional medicinal herbs in China. Saponin is the major active component in PN. The content of total saponins can reach to 12 %, and ginseng Saponin Rg1 and Rb1, Panax Notoginseng Saponin R1 are the highest. In addition, it contains other components of non- saponin, such as naphtha, flavonoid, glucide, etc. In recent years, PN is widely used to dialecticly therapy of medical and surgical diseases. The PN has not only the traditional efficacies of hemostasia, enriching the blood, detumescence and acesodyne, regulating the blood sugar and blood greasein in double directions, but also other efficacies, such as anti-thrombotic, anti-fibrosis active, anti-inflammation, anti-tumor, and so on. It plays a tremendous role in various kinds of Clinic applications. It has a broad application prospect in the future.In this paper, a systematical study on the process of the extraction and purification of Panax Notoginseng total saponin was given. Firstly, a method combining decompressing inner ebullition extraction and macroporous resin separation was developed to extract and purify total saponin of the Panax Notoginseng. Secondly, the optimal conditions of the extraction and purification were studied experimentally. Finally, the crystallization method was used to purify the saponin further. The results show that the processes of the extraction and purification in our experiments have specific advantages and higher purity and yield compared with some other traditional methods.Innovation points of this technic are: 1) the method combining decompressing inner ebullition extraction and macroporous resin separation has the advantages of fast speed extraction, omitting the processes of water precipitation or alcohol precipitation, higher yield and efficiency, and good product quality in comparison with traditional methods. 2) it improved the extraction method of the themosensitive component of Rbj. 3) applying double column crystallization method, we could get higher purity of Panax Notoginseng saponin and keep higher product yield. Then it is a good basis for further separation of saponin.

Related Dissertations

  1. Numerical Investigation of Effects of Boundary Layer Suction on the Performance of Diffusion Cascade,TH453
  2. Research on Automatic Detection Algorithm for Substructure Distress of Highway Pavement Based on SVM,U418.6
  3. The Flow Theroy Investigation of Compressor Cascade with Split,TK474.8
  4. Research of Question Answering System Based on the Analysis of Lexical and Semantic Meanings,TP391.1
  5. Research on Feature Extraction and Classification of Tongue Shape and Tooth-Marked Tongue in TCM Tongue Diagnosis,TP391.41
  6. Multi-currency Notes Technology Research and Implementation,TP391.41
  7. Synthesis and Resolution Property of N-(9-Fluorenylmethoxycarbonyl)-D-Tryptophan and D-Phenylalanine Imprinted Polymer,O631.3
  8. Experimental Study and Analyses of O2 -CO2 Production Based on Chemical Looping Method,O611.3
  9. Synthesis and Seperation of 1,1’-binaphthol,O625.3
  10. Studies on Extraction and Analysis of Fructooligosaccharides in Smallanthus Sonchifolius,TS255.1
  11. An Approach for Identifying a Plant Resistance Gene Based on the Random Forest,Q943
  12. Road extraction algorithm based on region segmentation of remote sensing image,TP751
  13. Study on the Extraction of Volatile Oil from Hangzhou White Chrysanthemum Morifolium and Its Application in Cigarettes,TS264.3
  14. Study on the Separation and Purification Way of Arctiin from Fructus Arctii and the Effect of Arctiin on the Growth of Mice C2C12 Cells,S853.7
  15. Identification of Marine Sreptomyces Sp. GY-4 and Researches on Its Antimicrobial Substances,Q936
  16. Prokaryotic Expression and Purification of Human Beta-Defensin-9,Q78
  17. The Supercritical Carbon Dioxide Extraction and Functional Quality Evaluation of Camellia Seed Oil,TS225.16
  18. Research on Identification System of Cashmere and Wool Fiber,TS101.921
  19. Study on Extraction,purification and Antioxidant Activity of Wheat Germ Polysaccharides,TS210.1
  20. Isolation, Purification and Antioxidant Activity of Proteins from Chinese Yam,TS255.1
  21. Protection Effects of Pu-er Green Tea Water Extraction Again Trans Fatty Acid,R285.5

CLC: > Medicine, health > Chinese Medicine > Of Pharmacy > Traditional Chinese medicine chemical > Separation and extraction of active ingredients
© 2012 www.DissertationTopic.Net  Mobile