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Studies on Chemical Constituents of Effective Parts of Anti-Inflammation and Analgesia in Urtica Angustifolia Fisch. Ex Hornem

Author: JuZhiHe
Tutor: WangDong;GuanFeng
School: Heilongjiang University of Traditional Chinese Medicine
Course: Of Pharmacy
Keywords: Angustifolium nettle Chemical composition Isorhamnetin Trans - hydroxy cinnamic acid Daucosterol
CLC: R284
Type: Master's thesis
Year: 2008
Downloads: 191
Quote: 1
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Abstract


Urticaceae Urtica the plant stenophylla nettle (Urtica angustifolia Fisch ex Hornem) is one of the main sources of the common folk medicine nettle has Qufeng , given shock Pinggan , Xiaoji laxative , and detoxification . The folk are widely used in the treatment of rheumatoid arthritis , post-natal convulsions , convulsions in children , urticaria , chronic bronchitis , diabetes , snake bites . The narrow leaf nettle is a perennial herb with very strong vitality , is widely distributed in the Black Kat Liao , Jin the Jilu and Inner Mongolia region , is very rich in natural resources , the development of high medicinal value and economic value waiting . Nettle in recent years , anti-inflammatory , anti-rheumatic effect attracted the attention of scholars from various countries , are more mature plants abroad for European production nettle . Not yet see the in-depth study of the narrow- leaf nettle date of the plant components study was limited in its Analysis of trace elements , especially its significant anti-rheumatic mechanism and substance basic research is still blank . Therefore, this article in its study , the research for the study, and its chemical composition will narrow leaf nettle pharmacology, efficacy and clinical depth research has important reference value . In this study, 95% of the narrow- leaf nettle ethanol extract chemical composition , from which 10 compounds were isolated using physicochemical methods and 1 < / sup> H- NMR 13 C-NMR, MS spectral method to identify five compounds , 5,7,4 ' - trihydroxy - 3'- methoxy - flavonols ( different mouse Li Su isorhamnetin ) , quercetin -3-O -β-D- glucopyranoside (quercetin-3-O-β-D-glucopyranoside), trans - hydroxy cinnamic acid (trans - 4 - hydroxycinnamic acid ) , kaempferol - 3- O -β - D - glucosidase (Kaempferol-3-O-β-D-glucoside), carrots glycosides ( daucosterol ) , , these five compounds are first separated from the narrow leaf nettle . In addition , several structures of the compounds identified work in progress . The results of this research laid the foundation for in-depth study of the narrow- leaf nettle when Heilongjiang rich nettle medicinal resources development and utilization of important scientific basis .

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