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The Influence Factors of Anastomotic Stricture Formation after Resection of Esophageal Carcinoma and the Therapy of Endoscopic Balloon Dilation

Author: LiFengYing
Tutor: MaShuRen
School: Dalian Medical University
Course: Internal Medicine
Keywords: Esophageal cancer Anastomotic stricture Logistic regression analysis Endoscopic Balloon dilatation
CLC: R735.1
Type: Master's thesis
Year: 2008
Downloads: 40
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Abstract


Objective: To investigate the factors that affect patients with esophageal anastomotic stricture formation and evaluation of clinical efficacy and the factors that affect the efficacy of endoscopic balloon dilation. Methods: A retrospective analysis of the clinical data of patients with esophageal cancer in January 2005 - May 2007 I underwent surgical treatment. Collect the patient's age, sex, duration of lesions, histological type, lesion length, clinical stage, surgical approach, anastomosis complications and postoperative treatment, logistic regression analysis of statistical applications. Postoperative anastomotic admitted in our hospital outpatient endoscopy center in January 2005 - January esophageal cancer, benign stricture underwent endoscopic dilation treatment, The postoperative endoscopic lipiodol angiography regular follow-up and the observation of the obstructive symptoms, quality of life and survival of Results: 112 cases of surgical treatment of patients with esophageal cancer, in addition to the two cases of anastomotic recurrence of cancer, 11 patients had anastomotic stenosis (9.82%), the median time of 2.5 months (1.0 months to 27 months) . Logistic regression analysis showed that: anastomosis (P = 0.022) and anastomotic site inflammation (P = 0.004) is consistent with the stenosis risk factors. The recent outpatient admitted 39 patients with benign anastomotic stenosis by endoscopic balloon dilatation, a total of 97 cases, an average of 2.5 visits / person, after the expansion of all patients with anastomosis stenosis symptoms was 100%, after treatment, the average diameter of anastomotic increased from 0.42 cm to 2.11 cm (P lt; 0.001). In addition to Weiss and a small amount of bleeding, and other serious complications. 18 cases of dilatation, dilation 2 times in seven cases, nine cases expansion three times, five cases were more than four times expansion. Efficiency of 97.4% (38/39), the effective rate of 51.28% (20/39). The efficacy of the method may stenosis, stenosis, expansion of the number of expansion time, anastomosis to mouth accompanied by inflammation. The follow-up observation of the 5 patients with tumor recurrence caused by anastomotic stenosis, 3 of them underwent endoscopic stenting. Conclusion: anastomosis, anastomotic site inflammation independent risk factor for esophageal cancer postoperative anastomotic stricture formation. Endoscopic balloon dilation treatment of esophageal anastomotic stricture after significant effect, factors that affect the expansion efficacy may be related to the stenosis, stenosis, surgery anastomotic reserves too small, expansion of the number of expansion time, consistent with inflammation of the mouth accompanied by relevant The method is simple, safe and reliable, good repeatability, is the preferred method of treatment of benign strictures after esophagectomy anastomotic.

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CLC: > Medicine, health > Oncology > Gastrointestinal Cancer > Esophageal tumors
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