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Objective: bronchial airways of asthmatic rats , colon , nose , skin and mucous membrane CD 4 , a CD > Determination of lymphocyte , looking for a correlation between the various tissues and organs , to find substances ties between the lung and colon , skin , nose , especially lung and Large Intestine \Methods: Immunohistochemical staining method to observe the various parts of the CD < / sub > . < / Sup> CD 8 lymphocytes change . Results: 1) Compared with normal group , the lung of asthmatic rats , colon , nasal tissue CD 4 expression were significantly higher than the normal group , a significant difference (P lt; 0.05), heart, spleen , skin tissue CD 4 expression was no statistical difference ( P gt ; 0.05) . Rat lung , colon , nose Organization CD 8 , were also significantly higher than the normal group , a significant difference ( P lt; 0.05 ) , while the two groups heart, spleen , skin tissue CD 8 expression there was no significant difference ( P gt; 0.05 ) ; 2 ) in normal rats six sites CD < sub > 4 , CD , 8 expression were significantly lower than the asthma group , normal rats lung, colon , nasal tissue of the CD 4 CD 8 expression was no significant difference ( P gt ; 0.05 ) ; 3 ) asthma group six sites in the rat CD 4 expression above the heart, spleen , skin , lung tissue , a statistical difference ( P lt; 0.05 ) . CD 8 expression , lung tissue above the heart, skin , significant difference ( P lt; 0.05 ) , the CD lung, colon , nasal tissue 4 , CD 8 of expression was no significant difference . Conclusions: 1) the lung in the asthma group , colorectal tissue CD 4 the the CD 8 the < / sub > . expression was significantly higher correlation ; 2 ) the mucosal immunization CD 4 CD 8 T lymphocytes may is part of the substance between the contact in the lung and colon .
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