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Background: Insomnia is common today, and its high incidence and increasing every year. After taking the drug resistance and long-term view of the side effects of the medication, acupuncture as an alternative therapy showed a unique advantage, effective drug with fewer side effects. A large number of acupuncture treatment for insomnia clinical studies of a variety of therapies to acupuncture and acupoints for a fresh start from the sleep wake cycle, to improve the efficacy of biological circadian rhythm. Clinical treatment of insomnia, and some acupuncturist night Acupuncture treatment effect treatment than during the day. Acupuncture intervention time, there are three randomized controlled clinical trials have shown that acupuncture is better than the morning, afternoon acupuncture treatment of insomnia, but not yet an acupuncture treatment studies of insomnia at night, for a clear night facilities for recovery of patients with insomnia circadian rhythm The impact, I tutor clinical experience - conditioning marrow method, the treatment of insomnia at EA, and set up the morning of the control group, and further explore the relationship between time and efficacy of acupuncture intervention. Objective: To compare the efficacy evening electro-acupuncture treatment of insomnia treatment of insomnia and morning EA differences. Methods: A prospective randomized controlled trial design, Guang An Men Hospital, Department of Cardiology, Endocrinology, acupuncture hospitalized patients for the study, 60 patients met the inclusion criteria not exclude the standard column insomnia patients were randomly divided into two groups in the evening The group of 30 patients, at 8:00 to 9:00 treated group of 30 patients in the morning, 8:00 am to 11:00 treated. Two groups are conditioning marrow law acupoints: Baihui, the Court of God, the first dimension (bilateral), on the YINTANG, Shenmen (bilateral), Sanyinjiao (bilateral), the on YINTANG down other points backward along by the flat spines, 5 minutes or so into the periosteum, the needle under arrest tight heaviness. Baihui and Shenting plus EA (1 ~ 3mA, 2Hz ~ 100Hz, etc. amplitude density wave), the needle for 20min, day 1, 5 times for one course, two courses of treatment, treatment interval of two days. During treatment, patients are encouraged to make without a hypnotic drug, also can be taken when necessary. Before treatment, 1 week, 2 Zhou observed PSQI score, sleep rate, during the day and sleep time and hypnotic drug use frequency times of change, the treatment of the first day record patients sleep rate, daytime sleep time, during treatment at any time recorded adverse reactions. Results: 60 people involved in a randomized, shedding two cases due to complications of disease progression, the evening group, the morning group off the two cases due to adverse events, the group in the evening, the morning group. Off cases of intent analysis. Results night group and morning groups could reduce PSQI score, improve sleep rate, two weeks after the two indicators were 9.93 ± 5.22, 70.83 ± 21.77%, and 13.07 ± 4.22 and 56.57 ± 19.83%, evening group better than morning group, the difference between groups was significant (P <0.05). Evening group one day can significantly improve patients' sleep rate (P <0.01), showed immediate effect, and the morning group immediate effect was not obvious (P ≥ 0.05). For evening group after treatment hypnotic drug use increased from 3.23 ± 3.22 times / week decreased to 1.53 ± 2.50 times / week, the difference was significant (P <0.01), the morning group had no significant change (P ≥ 0.05), before and after treatment two groups during the day and sleep time no significant change (P ≥ 0.05). Conclusion: night electro-acupuncture can significantly reduce insomnia patients PSQI score, improve sleep rate, reduce the use of hypnotic drugs, and with immediate effect, the treatment is better than the morning.
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